BOSENTAN

BOSENTAN: BOSENTAN is a medication used in the treatment of pulmonary arterial hypertension (PAH). It belongs to a class of drugs called endothelin receptor antagonists.

The drug works by blocking the action of endothelin, a substance that causes blood vessels to constrict, leading to increased blood pressure. By inhibiting the endothelin receptors, BOSENTAN helps to dilate the blood vessels, reducing blood pressure in the lungs.

BOSENTAN is usually taken orally, with or without food, and the dosage prescribed varies depending on the patient’s weight, medical condition, and response to the treatment. It is typically started at a low dose and gradually increased to minimize the risk of side effects.

Some common side effects of BOSENTAN include headache, flushing, nasal congestion, and upset stomach. These side effects are usually mild and transient. However, more serious but rare side effects may occur, such as liver damage, anemia, and fluid retention. Regular monitoring of liver function and blood cell counts is necessary during treatment with BOSENTAN.

It is important to note that BOSENTAN can cause birth defects, so it should not be used by pregnant women or women planning to become pregnant. Additionally, it can decrease the effectiveness of hormonal contraceptives, so alternative methods of contraception should be used while taking this medication.

In summary, BOSENTAN is a medication used to treat pulmonary arterial hypertension. It works by blocking endothelin receptors, dilating the blood vessels, and reducing blood pressure in the lungs. While it can have side effects, they are usually mild and transient. However, close monitoring is necessary, and the medication should not be used during pregnancy.