CALCIUM CARBONATE + METHYLCOBALAMIN + VITAMIN D3 (CHOLECALCIFEROL) + L-METHYLFOLATE + PYRIDOXAL-5-PHOSPATE
Calcium Carbonate: Calcium Carbonate is a medication that is commonly used to treat conditions caused by low calcium levels in the body, such as osteoporosis and certain cases of hypoparathyroidism. It is also used as an antacid to relieve symptoms of heartburn, acid indigestion, and upset stomach.
The main action of Calcium Carbonate is to provide the body with supplemental calcium. Calcium is an essential mineral that plays a vital role in bone health and functioning of the nervous system. When calcium levels are low, Calcium Carbonate can help replenish these levels and support normal bodily functions.
The recommended dose of Calcium Carbonate varies depending on the individual’s age, condition, and purpose of use. As a dietary supplement or antacid, it is typically taken 1-2 times daily with meals. However, it is important to follow the instructions provided by your healthcare provider or the product label.
Common side effects of Calcium Carbonate include constipation, gas, and bloating. In rare cases, high doses or prolonged use may lead to hypercalcemia (high levels of calcium in the blood) or the formation of kidney stones. It is important to inform your doctor if you experience any persistent or severe side effects.
It is worth noting that calcium carbonate may interact with certain medications, such as certain antibiotics, bisphosphonates, and iron supplements. Therefore, it is important to inform your healthcare provider about all medications you are currently taking to avoid any potential drug interactions.
Overall, Calcium Carbonate is a widely used medication to treat calcium deficiency and related conditions. However, it is essential to use it as directed by a healthcare professional and be aware of potential side effects and drug interactions.
Methylcobalamin: Methylcobalamin, a form of vitamin B12, is a medication mainly used to treat vitamin B12 deficiency. It is an essential nutrient that plays a crucial role in the formation of red blood cells, DNA synthesis, and proper nerve function. Methylcobalamin is available in the form of oral tablets, sublingual tablets, injections, and nasal sprays.
The primary mechanism of action of Methylcobalamin is its conversion into coenzyme B12 to participate in various enzymatic reactions in the body. It is involved in the conversion of homocysteine to methionine, which helps in DNA synthesis and red blood cell production. Methylcobalamin also contributes to myelin sheath formation, which protects nerve cells and ensures their proper functioning.
The dosage of Methylcobalamin varies depending on the individual’s age, medical condition, and the severity of B12 deficiency. A common oral dose for adults is usually 1000-2000 mcg per day. Sublingual tablets are also available, which are dissolved under the tongue for better absorption. Injections are typically administered intramuscularly, and the frequency of injections ranges from once daily to once every few weeks, depending on the severity of the deficiency.
Methylcobalamin is generally safe and well-tolerated. However, like any medication, it can cause side effects in some individuals. Common side effects may include mild diarrhea, nausea, headache, or skin rash. In rare cases, allergic reactions or anaphylaxis may occur, which require immediate medical attention. High doses of Methylcobalamin may exacerbate certain medical conditions, such as congestive heart failure or renal impairment. Therefore, it is important to consult a healthcare professional before starting Methylcobalamin treatment, especially if you have any underlying medical conditions or are taking any other medications.
Vitamin D3 (cholecalciferol): Drug: Vitamin D3 (cholecalciferol)
Use: Vitamin D3 is a form of vitamin D that is used to treat or prevent vitamin D deficiency. It is also used to support bone health and calcium absorption in the body.
Mechanism of action: Vitamin D3 functions as a prohormone, which means it is converted into an active hormone in the body. Once absorbed, it undergoes metabolism in the liver and kidneys to form calcitriol, the active form of vitamin D. Calcitriol acts as a regulator of calcium and phosphate metabolism and helps maintain healthy levels of these minerals in the body. It facilitates the absorption of calcium from the intestines, promotes bone formation by osteoblasts, and inhibits the release of parathyroid hormone (PTH) from the parathyroid glands.
Dose: The recommended dose of vitamin D3 depends on the individual’s age and specific condition. For the prevention and treatment of vitamin D deficiency, the typical dose is 400 to 1000 international units (IU) daily for infants, children, and adults. Higher doses may be required for individuals with severe deficiency or certain medical conditions, and these doses are determined by a healthcare professional.
Side effects: Vitamin D3 is generally safe when taken in recommended doses. However, excessive intake of vitamin D3 can lead to an overdose, which may cause symptoms such as nausea, vomiting, constipation, loss of appetite, excessive thirst, frequent urination, weakness, fatigue, confusion, and kidney problems. Extremely high doses of vitamin D3 over a prolonged period can result in hypercalcemia (elevated calcium levels in the blood), which can lead to bone pain, kidney stones, and organ damage.
It is important to consult a healthcare professional before starting any vitamin D3 supplementation, especially if you have certain medical conditions or are taking other medications, as interactions and individual requirements may vary.
L-Methylfolate: L-Methylfolate is a medical supplement that is used to treat or prevent folate deficiency. It is a form of folic acid, which is a B vitamin that is necessary for the production of red blood cells and DNA.
The main mechanism of action for L-Methylfolate is that it provides the body with an active form of folate that can be easily used by the cells. Unlike regular folic acid, L-Methylfolate does not need to be converted in the body and can be readily absorbed and utilized for its biological functions.
The recommended dose of L-Methylfolate varies depending on the individual’s needs and the specific condition being treated. Generally, the usual dose for a folate deficiency is 1-2.5 milligrams per day. However, it is important to follow the instructions provided by the healthcare provider or refer to the product label.
As with any medication, L-Methylfolate may cause certain side effects. Common side effects include nausea, loss of appetite, abdominal discomfort, bloating, and a bitter or unpleasant taste in the mouth. In rare cases, allergic reactions may occur, which may manifest as rash, itching, swelling, severe dizziness, or difficulty breathing. It is important to seek medical attention if any severe side effects are experienced.
L-Methylfolate is generally well-tolerated and has a good safety profile. However, it is important to consult with a healthcare professional before starting L-Methylfolate to ensure it is suitable for the individual’s specific needs and to avoid any potential drug interactions or contraindications.
Pyridoxal-5-Phospate: Pyridoxal-5-Phosphate (PLP) is a biologically active form of Vitamin B6. It is considered as a coenzyme that plays a crucial role in various enzymatic reactions in the body.
PLP is used in the treatment of Vitamin B6 deficiency, as well as certain conditions that are responsive to Vitamin B6 supplementation such as peripheral neuropathy, premenstrual syndrome (PMS), and certain types of epilepsy.
The mechanism of action of PLP involves its conversion to the active form, pyridoxal phosphate (PLP), which acts as a coenzyme for various enzymes involved in the metabolism of amino acids, neurotransmitters, and glycogen. PLP is involved in the synthesis of neurotransmitters such as serotonin, dopamine, and GABA, which are important for the proper functioning of the nervous system.
The recommended dose of PLP varies depending on the specific condition being treated and individual factors. It is important to consult with a healthcare professional for the appropriate dosage.
Side effects of PLP are rare but can include nausea, vomiting, headache, sleepiness, or allergic reactions. High doses of PLP over a prolonged period may lead to sensory neuropathy or neurological impairment.
It is important to note that PLP should only be taken under the supervision of a healthcare professional, especially if you have any underlying medical conditions or are taking other medications, as there may be potential interactions.
