CHLORHEXIDINE

CHLORHEXIDINE: Chlorhexidine is an antiseptic and disinfectant drug that is commonly used for a variety of purposes. It is available in different forms such as rinses, solutions, gels, and wipes.

Use: Chlorhexidine is used for various purposes including oral care, surgical site cleansing, wound care, skin disinfection, and prevention of infections in medical devices such as catheters. It is also used in the treatment of certain skin conditions such as acne.

Mechanism of action: Chlorhexidine works by disrupting the integrity of the bacterial cell wall, thereby inhibiting bacterial growth and killing the microorganisms. It has a broad-spectrum of activity against both gram-positive and gram-negative bacteria, as well as fungi.

Dose: The dose of chlorhexidine depends on the form and purpose of use. For oral care, a common dose is 0.12% – 0.2% chlorhexidine mouthwash, which is usually used twice daily for about 30 seconds. For surgical site cleansing, the concentration and duration of use may vary based on the specific procedure.

Side effects: Chlorhexidine is generally well-tolerated, but some individuals may experience mild to moderate side effects. These can include temporary discoloration of teeth or tongue, altered taste sensation, mouth or throat irritation, and dryness. Rarely, allergic reactions such as rash or swelling may occur. Prolonged use of chlorhexidine can also lead to an overgrowth of certain microorganisms, resulting in oral or vaginal yeast infections.

It is important to note that chlorhexidine should not be swallowed and may interact with certain dental materials such as toothpaste containing sodium fluoride. It is recommended to consult a healthcare professional for specific guidance on the appropriate use and dosage of chlorhexidine based on individual needs.