DEXTROMETHORPHAN + TRIPROLIDINE
Dextromethorphan: Dextromethorphan is a medication primarily used as a cough suppressant. It is commonly found in over-the-counter cold and cough medicines. It is recommended for the temporary relief of coughing caused by minor throat and bronchial irritation.
The mechanism of action of dextromethorphan is not fully understood, but it is believed to affect the cough reflex in the medulla oblongata of the brain. It acts as an antagonist at the N-methyl-D-aspartate (NMDA) receptor, which is involved in signal transmission between nerve cells.
The dosage of dextromethorphan can vary depending on factors such as age, weight, and the severity of symptoms. Generally, for adults and children above 12 years of age, the recommended dose is 10-20 mg every 4-6 hours, with a maximum daily dose of 120 mg. For children aged 6-12 years, the dose is usually 5-10 mg every 4-6 hours, with a maximum daily dose of 60 mg.
While dextromethorphan is generally well-tolerated, it can cause side effects in some individuals. Common side effects include drowsiness, dizziness, upset stomach, nausea, and vomiting. Rare but serious side effects may include allergic reactions, difficulty breathing, confusion, hallucinations, and irregular heartbeat. It is important to follow the recommended dosage guidelines and consult a healthcare professional if any concerning side effects occur.
It is worth noting that dextromethorphan abuse has been reported, as it can produce euphoric effects and hallucinations when taken in large doses. To prevent misuse, many countries regulate the sale of dextromethorphan-containing products, requiring them to be sold behind the counter or with age restrictions.
Triprolidine: Triprolidine is an antihistamine drug that is commonly used to treat symptoms of allergies, such as sneezing, itching, watery eyes, and runny nose. It is also used as a sedative in cough syrups to help relieve sleeplessness associated with colds and allergies.
The mechanism of action of triprolidine involves blocking the effects of histamine, which is a chemical released by the body during an allergic reaction. By blocking histamine receptors, triprolidine prevents the symptoms of allergies from occurring.
Triprolidine is usually taken orally in the form of tablets or capsules. The recommended dose for adults and children above the age of 12 is usually 2.5 to 5 mg every 4 to 6 hours as needed. However, the specific dosage may vary depending on individual factors, such as the severity of symptoms and the patient’s response to treatment. It is important to follow the instructions provided by the healthcare professional or the instructions on the product packaging.
As with any medication, triprolidine may cause side effects. Common side effects include drowsiness, dizziness, dry mouth, blurred vision, constipation, and difficulty urinating. These side effects are usually mild and temporary. However, if they persist or become severe, it is important to consult a healthcare professional.
In rare cases, triprolidine may cause more serious side effects, such as rapid or irregular heartbeat, hallucinations, confusion, difficulty breathing, or severe allergic reactions. If any of these side effects occur, immediate medical attention should be sought.
It is important to note that triprolidine may interact with other medications or substances, including alcohol, causing increased drowsiness or impairment. Therefore, it is advisable to inform your healthcare professional about all the medications, supplements, or substances you are using before starting triprolidine.
In conclusion, triprolidine is an antihistamine drug used to relieve symptoms of allergies and as a sedative in cough syrups. It works by blocking the effects of histamine in the body. The recommended dose varies depending on individual factors, and common side effects may include drowsiness, dry mouth, and blurred vision.
