DORZOLAMIDE HYDROCHLORIDE

DORZOLAMIDE HYDROCHLORIDE: Dorzolamide hydrochloride is a medication primarily used to lower intraocular pressure in individuals with open-angle glaucoma or ocular hypertension, conditions that can lead to optic nerve damage and vision loss.

The mechanism of action of dorzolamide hydrochloride involves inhibition of the enzyme carbonic anhydrase II, which is found in the ciliary processes of the eye. By inhibiting carbonic anhydrase II, dorzolamide hydrochloride reduces the production of aqueous humor in the eye, thereby decreasing intraocular pressure.

The drug is available as eye drops and is typically administered twice a day. The recommended dose is one drop in the affected eye(s) in the morning and one drop in the evening. It is important to follow the dosage instructions provided by the prescribing healthcare professional.

Common side effects of dorzolamide hydrochloride eye drops include a bitter or metallic taste in the mouth, eye discomfort or irritation, blurred vision, and redness or swelling of the eye. Some individuals may also experience dry eyes, eyelid reactions, or allergic reactions such as itching, hives, or difficulty breathing. It is important to consult a healthcare provider if any side effects are persistent or severe.

Dorzolamide hydrochloride may interact with other medications, so it is important to inform a healthcare professional of any other drugs being taken. It is also necessary for individuals with certain medical conditions, such as kidney disease, liver disease, or a sulfa allergy, to exercise caution or avoid using dorzolamide hydrochloride.