EZETIMIBE

EZETIMIBE: Drug: Ezetimibe
Brand Names: Zetia, Ezetrol

Description:
Ezetimibe is a prescription medication used in the treatment of high cholesterol levels in the blood. It belongs to a class of drugs called cholesterol absorption inhibitors.

Use:
Ezetimibe is primarily used to lower LDL cholesterol (commonly known as “bad cholesterol”) levels in the blood. It is often prescribed alongside other cholesterol-lowering medications such as statins. By reducing LDL cholesterol levels, Ezetimibe helps to reduce the risk of heart disease, heart attacks, and stroke.

Mechanism of Action:
Ezetimibe works by inhibiting the absorption of cholesterol from the small intestine. It specifically targets the Niemann-Pick C1-Like 1 (NPC1L1) protein, which is responsible for transporting cholesterol into the bloodstream. By blocking this protein, Ezetimibe reduces the amount of cholesterol that can be absorbed from the diet, leading to lower cholesterol levels in the bloodstream.

Dose:
The usual recommended dose of Ezetimibe is 10 mg once daily. It can be taken with or without food, at any time of the day. The medication should be taken regularly to achieve the maximum benefit.

Side Effects:
Common side effects of Ezetimibe may include:
1. Excessive tiredness or weakness
2. Stomach pain or cramps
3. Diarrhea
4. Joint pain
5. Allergic reactions like rash, itching, or swelling

However, serious side effects are rare. Contact a healthcare professional immediately if you experience symptoms such as severe stomach pain, muscle pain or tenderness, or dark-colored urine.

It is important to note that Ezetimibe is usually well-tolerated, but it may interact with other medications or medical conditions. It is always recommended to consult with a healthcare provider or pharmacist for personalized advice and guidance.