FLUNARIZINE

FLUNARIZINE: Flunarizine is a drug that belongs to the class of calcium channel blockers. It is primarily used for the prevention of migraine headaches and the treatment of vertigo associated with Meniere’s disease.

The mechanism of action of flunarizine involves its ability to block calcium channels in the smooth muscles of blood vessels and the inner ear. By doing so, it reduces the constriction of blood vessels and suppresses the release of certain neurotransmitters involved in the development of migraines and vertigo.

The typical dose of flunarizine for migraine prevention is 5-10 mg per day, taken orally. It is usually started at a low dose and gradually increased as tolerated, under the guidance of a healthcare professional. The treatment duration varies depending on individual response.

As with any medication, there are potential side effects associated with flunarizine. Common side effects include drowsiness, weight gain, fatigue, depression, and dry mouth. Less frequently, it may cause extrapyramidal symptoms such as involuntary movements or tremors. Long-term use of flunarizine has been associated with changes in mood and depressive symptoms in some individuals.

It is important to note that flunarizine may interact with other medications, so it is crucial to inform your healthcare provider about any other drugs you are taking. Additionally, pregnant women or those planning to become pregnant should discuss the potential risks and benefits of using flunarizine, as it may not be suitable during pregnancy due to possible effects on the developing fetus.

Overall, flunarizine is an effective medication for the prevention of migraines and treatment of vertigo, but its use should be carefully monitored by a healthcare professional due to its potential side effects and drug interactions.