FOLIC ACID + CALCIUM + NICOTINAMIDE + THIAMINE MONONITRATE + ALPHA LIPOIC ACID + MECOBALAMIN + PYRIDOXINE HYDROCHLORIDE + CHROMIUM PICOLINATE
Folic Acid: Folic Acid is a synthetic form of vitamin B9, also known as folate. It is an essential nutrient that our bodies need to produce and maintain new cells, including red blood cells. Folic Acid is typically used as a dietary supplement to treat or prevent folate deficiency.
The mechanism of action of Folic Acid involves its conversion to its active form, which is called tetrahydrofolic acid. This active form is necessary for the synthesis of DNA, RNA, and certain amino acids. Folic Acid is crucial for cell division and growth, and plays a vital role in the development of the fetal neural tube during early pregnancy.
The recommended dose of Folic Acid varies depending on the individual’s age and condition. For most adults, the recommended daily intake is around 400-800 micrograms (mcg). Pregnant women or those planning to become pregnant are often advised to take higher doses, typically around 600-800 mcg per day.
Folic Acid is generally safe and well-tolerated. However, like any medication, it may have side effects. Some common side effects of Folic Acid include nausea, loss of appetite, bloating, gas, and a bitter or bad taste in the mouth. These side effects are usually mild and resolve on their own.
Rarely, high doses of Folic Acid can mask the symptoms of vitamin B12 deficiency, which can lead to nerve damage if untreated. Therefore, it’s important to ensure an adequate intake of vitamin B12 while taking Folic Acid supplements, especially in older adults.
It’s worth mentioning that Folic Acid supplementation is particularly important for women who are pregnant or planning to become pregnant. Adequate levels of Folic Acid during pregnancy can help prevent neural tube defects in the developing baby, such as spina bifida.
It is always recommended to consult with a healthcare professional before starting any new medication or supplement to ensure it is appropriate for your individual needs and to discuss the proper dosage.
Calcium: Drug: Calcium
Use: Calcium is a mineral that is essential for various bodily functions. It is primarily used to treat or prevent calcium deficiency, which can lead to conditions like osteoporosis, hypoparathyroidism, and rickets. It may also be prescribed for certain conditions like hyperkalemia, heartburn, and as an adjunctive therapy in certain cases of high blood pressure.
Mechanism of Action: Calcium plays a vital role in numerous physiological processes, including bone formation, nerve transmission, muscle contraction, and blood clotting. When administered as a medication, calcium supplements work by increasing the calcium levels in the body, addressing deficiencies and promoting normal functioning.
Dose: The recommended dose of calcium varies depending on the individual’s age, gender, and specific medical condition. It is typically taken orally in the form of calcium carbonate or calcium citrate tablets. The dosage may range from 500 to 1500 mg per day, and it is often split into multiple doses to enhance absorption. It is essential to follow the prescribed dosage as instructed by the healthcare provider.
Side Effects: While calcium is generally safe when taken at recommended doses, some individuals may experience side effects. Common side effects include constipation, gas, bloating, and an upset stomach. In rare cases, high doses or prolonged use of calcium supplements can lead to hypercalcemia, a condition characterized by excessive calcium levels in the blood. Symptoms of hypercalcemia may include nausea, vomiting, increased thirst, frequent urination, and confusion. It is important to seek medical attention if any severe side effects occur. Additionally, individuals with certain medical conditions such as hyperparathyroidism or kidney disease should exercise caution when taking calcium supplements and consult their healthcare provider for appropriate dosage adjustments.
Nicotinamide: Nicotinamide, also known as niacinamide, is a form of vitamin B3 that is commonly used in medical and cosmetic products. It is available as both a prescription medication and an over-the-counter dietary supplement.
Nicotinamide is used to treat and prevent niacin deficiency, which can result in a condition called pellagra. It is also used as an adjunct therapy for certain dermatological conditions such as acne, rosacea, and bullous pemphigoid. Additionally, it is used in combination with other medications for the treatment of certain autoimmune disorders like rheumatoid arthritis.
The exact mechanism of action of nicotinamide is not fully understood, but it is believed to work by increasing the production of certain enzymes involved in cellular energy metabolism. It also has anti-inflammatory properties and can help prevent the breakdown of collagen in the skin.
For the treatment of niacin deficiency or as a dietary supplement, the recommended dose of nicotinamide is typically 250 to 500 mg taken orally once or twice daily. For dermatological conditions, the dose may vary depending on the severity of the condition and individual response. It is important to follow the instructions provided by the healthcare provider or read and follow the product label carefully.
Common side effects of nicotinamide are generally mild and include headache, dizziness, flushing, upset stomach, and allergic reactions such as rash or itching. Rarely, it may cause more serious side effects such as hepatotoxicity (liver damage) or hyperglycemia (high blood sugar levels). It is important to report any severe or persistent side effects to a healthcare professional.
Nicotinamide is generally considered safe when used as directed, but it is always recommended to consult with a healthcare provider before starting any new medication or supplement, especially if you have any underlying medical conditions or are taking other medications.
Thiamine Mononitrate: Thiamine mononitrate is a synthetic form of thiamine, also known as vitamin B1. It is commonly used as a dietary supplement to prevent or treat thiamine deficiency. Thiamine is essential for the proper functioning of the body, as it plays a crucial role in converting carbohydrates into energy and maintaining a healthy nervous system.
The mechanism of action of thiamine mononitrate involves its conversion into thiamine pyrophosphate (TPP), which functions as a coenzyme. TPP is involved in various enzymatic reactions that are important for the metabolism of glucose and the production of energy. By providing the body with an adequate supply of thiamine, thiamine mononitrate can help reverse the symptoms of thiamine deficiency and support normal bodily functions.
The recommended dose of thiamine mononitrate varies depending on the individual’s age, sex, and medical condition. For adults, a typical dose is 1.5 to 2.5 milligrams per day. However, the specific dosage should be determined by a healthcare professional based on the individual’s needs.
Side effects of thiamine mononitrate are rare but can occur in some individuals. These may include mild stomach upset, nausea, vomiting, headache, and skin rash. In rare cases, allergic reactions such as itching, hives, swelling, and difficulty breathing may occur. If any severe or persistent side effects are experienced, medical attention should be sought immediately.
It is important to note that thiamine mononitrate is not recommended for self-diagnosis or self-treatment. It should be used under the guidance of a healthcare professional and as part of a comprehensive treatment plan for thiamine deficiency or other specific medical conditions.
Alpha Lipoic Acid: Alpha Lipoic Acid (ALA) is a naturally occurring antioxidant that is sometimes referred to as the “universal antioxidant” because of its ability to dissolve in both water and fat. It plays a crucial role in energy production within the cells and also helps to regenerate other antioxidants like vitamins C and E.
ALA has several uses and benefits. It is primarily used as a dietary supplement to support overall health and well-being. It is believed to have potential antioxidant properties that can protect cells from damage caused by free radicals. Additionally, ALA is used as a nutritional supplement in the management of certain conditions, such as diabetic neuropathy, where it may help improve nerve function and reduce symptoms like numbness and tingling.
The mechanism of action of ALA involves its ability to scavenge and neutralize free radicals, which are unstable molecules responsible for oxidative damage in the body. ALA can also enhance the antioxidant capacity of other substances like glutathione, further protecting the cells from damage. Furthermore, ALA has been shown to have anti-inflammatory effects and may influence certain signaling pathways involved in various disease processes.
The typical dose of ALA varies depending on the purpose of use. When used as a dietary supplement, the recommended dosage is usually between 200-600 mg per day. For diabetic neuropathy, higher doses of 600-1800 mg per day may be prescribed under medical supervision.
While ALA is generally considered safe for most people when taken orally in appropriate doses, it may cause a few side effects. These can include gastrointestinal symptoms like nausea, stomach upset, and diarrhea. In rare cases, allergic reactions such as rash, itching, or difficulty breathing may occur. It is important to discuss the use of ALA with a healthcare professional, especially if you have any existing health conditions or are taking other medications, as there may be potential interactions or contraindications to consider.
Overall, Alpha Lipoic Acid is a promising antioxidant supplement that supports overall health and may have specific benefits in certain conditions like diabetic neuropathy. However, it is always recommended to consult with a healthcare professional before starting any new supplement or medication.
Mecobalamin: Mecobalamin is a drug that belongs to the vitamin B12 group. It is an active form of vitamin B12 and plays a crucial role in the normal functioning of the nervous system and the production of red blood cells.
Mecobalamin is used to treat various conditions, primarily those related to vitamin B12 deficiency. It is commonly prescribed for people with pernicious anemia, a condition caused by the inability to absorb vitamin B12 from the gastrointestinal tract. Mecobalamin is also used in the treatment of neuropathies, such as diabetic neuropathy, and other conditions that result in nerve damage.
The exact mechanism of action of Mecobalamin is not fully understood. However, it is believed to work by aiding in the synthesis of DNA, RNA, and myelin, which is a protective covering that surrounds nerves. It also helps in the formation of red blood cells and aids in maintaining the health of nerve cells.
The usual dose of Mecobalamin varies depending on the indication and individual patient requirements. It is available as an oral tablet, sublingual tablet, or as an injectable formulation. The recommended dose range for adults is usually between 500 to 1500 mcg per day. The dosing schedule and duration of treatment should be determined by a healthcare professional.
As with any medication, Mecobalamin can have side effects. Common side effects may include diarrhea, itching, rashes, headache, dizziness, and upset stomach. Some individuals may also experience an allergic reaction to the drug, which may include symptoms such as difficulty breathing, swelling of the face or throat, or hives. If any severe or persistent side effects occur, it is important to seek immediate medical attention.
Overall, Mecobalamin is a beneficial drug for individuals with vitamin B12 deficiency or neuropathic conditions. However, it is essential to use it as directed by a healthcare professional and to report any side effects to ensure its safe and effective use.
Pyridoxine Hydrochloride: Pyridoxine hydrochloride, also known as vitamin B6, is a water-soluble vitamin that is essential for the proper functioning of the body. It is commonly used as a dietary supplement to treat or prevent vitamin B6 deficiency.
Pyridoxine hydrochloride acts as a coenzyme in various enzymatic reactions in the body. It plays a crucial role in the metabolism of amino acids, carbohydrates, and lipids. It is also involved in the production of neurotransmitters such as serotonin, norepinephrine, and dopamine, which are important for mood regulation.
The appropriate dose of pyridoxine hydrochloride may vary depending on the age, gender, and specific medical condition of the individual. For adults, the recommended daily intake ranges from 1.3 mg to 1.7 mg, while for pregnant and lactating women, it is slightly higher at 1.9 mg to 2.0 mg.
Most people can tolerate pyridoxine hydrochloride without experiencing any significant side effects. However, excessive intake of pyridoxine hydrochloride can lead to neurological symptoms such as numbness, tingling, and difficulty coordinating movements. This condition, known as peripheral neuropathy, is usually reversible when the intake of pyridoxine hydrochloride is reduced.
In rare cases, very high doses of pyridoxine hydrochloride may cause sensory neuropathy, which can lead to loss of reflexes, muscle weakness, and difficulty walking. It is important to consult a healthcare professional before taking high doses of pyridoxine hydrochloride.
Some individuals may also experience gastrointestinal side effects such as nausea, vomiting, abdominal pain, and diarrhea. These side effects are usually mild and temporary.
It is worth noting that pyridoxine hydrochloride may interact with certain medications, such as certain anticonvulsants, and decrease their effectiveness. Therefore, it is important to inform your healthcare provider about all the medications you are currently taking before starting pyridoxine hydrochloride supplementation.
Overall, pyridoxine hydrochloride is an essential vitamin that is widely used to prevent or treat vitamin B6 deficiency. It is generally safe when taken in appropriate doses, but excessive intake should be avoided to prevent potential side effects.
Chromium Picolinate: Chromium Picolinate is a dietary supplement that contains the essential mineral chromium in the form of picolinic acid. It is commonly used for its potential benefits in improving blood sugar control and aiding in weight loss.
The primary mechanism of action of Chromium Picolinate is believed to be its ability to enhance insulin sensitivity. Insulin is a hormone that plays a crucial role in regulating blood sugar levels. By increasing insulin sensitivity, chromium picolinate may help improve the body’s ability to utilize glucose effectively, leading to better blood sugar control. This can be particularly beneficial for individuals with diabetes or insulin resistance.
The recommended dose of Chromium Picolinate varies depending on the specific needs of the individual. However, the typical range for supplementation is typically around 200-1000 mcg per day. It is important to follow the instructions provided on the product label or consult a healthcare professional for personalized guidance.
Although generally considered safe when taken in recommended doses, Chromium Picolinate may cause some side effects. These can include digestive issues such as stomach discomfort, nausea, diarrhea, and headaches. In rare cases, high doses of chromium picolinate may lead to kidney problems or liver damage. It is advisable to consult a healthcare professional before starting any new supplement and to inform them of any pre-existing medical conditions or medications being taken.
It is worth noting that while several studies suggest potential benefits of chromium picolinate, evidence is still limited and more research is needed to fully understand its effects and long-term safety. Therefore, it is always best to use dietary supplements under the guidance of a healthcare professional.
