FOLIC ACID + PYRIDOXINE (VITAMIN B6) + BENFOTIAMINE + ALPHA LIPOIC ACID + CHROMIUM PICOLINATE + METHYCOBALAMIN + MYO-INOSITOL
Folic Acid: Drug: Folic Acid
Folic Acid is a synthetic form of folate, which is a water-soluble B-vitamin. It is also known as Vitamin B9. Folic Acid is essential for the production and maintenance of new cells in the body, including red blood cells.
Use: Folic Acid is commonly prescribed to treat and prevent a deficiency of folate in the body. It is often used to support the treatment of megaloblastic anemia, which is a type of anemia caused by a deficiency in folate or vitamin B12. Folic Acid supplementation is also recommended for women who are pregnant or planning to become pregnant to prevent certain birth defects, such as neural tube defects.
Mechanism of Action: Folic Acid plays a crucial role in the synthesis and repair of DNA, cell division, and growth. It is involved in multiple metabolic pathways, particularly in the production of nucleotides, which are the building blocks of DNA and RNA. Folic Acid is converted into its active forms, such as 5-methyltetrahydrofolate, in the body, which then participate in various enzymatic reactions.
Dose: The recommended daily dosage of Folic Acid may vary depending on the individual’s age, health condition, and reason for use. For adults, the usual daily dose ranges from 400 to 800 micrograms (mcg). Pregnant women are often advised to take higher doses, around 600 to 800 mcg per day. It is important to follow the dosage instructions provided by the healthcare professional or as indicated on the packaging.
Side Effects: Folic Acid is generally safe and well-tolerated when taken in recommended doses. However, some individuals may experience mild side effects including nausea, loss of appetite, bloating, gas, and a bitter or unpleasant taste in the mouth. In rare cases, allergic reactions such as rash, itching, or swelling of the face, tongue, or throat may occur. High doses of Folic Acid may also mask the symptoms of vitamin B12 deficiency or lead to complications in individuals with vitamin B12 deficiency.
It is crucial to consult with a healthcare professional before starting any new medication, including Folic Acid, to determine the appropriate dosage, duration of treatment, and to discuss potential interactions or contraindications with other medications.
Pyridoxine (vitamin B6): Pyridoxine, also known as vitamin B6, is a water-soluble vitamin that plays an essential role in various bodily functions.
Use: Pyridoxine is primarily used as a dietary supplement to treat or prevent vitamin B6 deficiency. It may also be prescribed to alleviate symptoms associated with certain conditions such as premenstrual syndrome (PMS), morning sickness during pregnancy, and some forms of anemia. Additionally, pyridoxine is sometimes used as an adjunct treatment for certain neurological disorders.
Mechanism of action: Pyridoxine is a cofactor in many enzymatic reactions involved in the metabolism of proteins, carbohydrates, and fats. It is particularly important for the synthesis of neurotransmitters such as serotonin, dopamine, and gamma-aminobutyric acid (GABA). By participating in these reactions, pyridoxine helps maintain normal nervous system function and supports the production of red blood cells.
Dose: The recommended daily intake of pyridoxine varies depending on age, gender, and specific needs. For most adults, the recommended dietary allowance (RDA) of pyridoxine ranges from 1.3 to 1.7 milligrams per day. However, higher doses may be prescribed in the case of deficiency or specific medical conditions.
Side effects: Pyridoxine is considered safe when taken within the recommended dosage range. However, very high doses (over 200 mg per day) or long-term use may lead to peripheral sensory neuropathy. This condition is characterized by numbness, tingling, or pain in the hands and feet. Other potential side effects of pyridoxine include nausea, vomiting, headache, and sleep disturbances. In rare cases, hypersensitivity reactions may occur. It is important to consult a healthcare professional before starting pyridoxine supplementation to determine the appropriate dosage and to discuss potential interactions with other medications.
Benfotiamine: Benfotiamine is a synthetic form of thiamine, also known as vitamin B1. It is primarily used as a dietary supplement in the treatment of various conditions associated with thiamine deficiency, such as neuropathy, diabetes, and Alzheimer’s disease.
The mechanism of action of benfotiamine involves its ability to increase the level of thiamine pyrophosphate (TPP), the active form of vitamin B1, in the body. This increase in TPP helps promote the normal functioning of enzymes that play a vital role in carbohydrate metabolism, nerve function, and cellular energy production.
The recommended dose of benfotiamine varies depending on the condition being treated. For diabetic neuropathy, the usual dose is 300 mg per day, divided into three doses. For other conditions, the daily dose typically ranges from 150-600 mg, also divided into multiple doses. It is advisable to consult a healthcare professional for the appropriate dosage based on individual needs.
Benfotiamine is generally considered safe when taken at recommended doses. However, some mild side effects may occur, including upset stomach, diarrhea, and skin rash. These side effects are usually temporary and resolve on their own. If any severe or persistent side effects are experienced, it is important to seek medical attention.
It’s worth noting that benfotiamine may interact with certain medications, such as diuretics, anticonvulsants, and drugs that lower blood sugar levels. Therefore, it is important to inform healthcare providers about all the medications, supplements, and medical conditions before starting benfotiamine.
Overall, benfotiamine is a supplement that can be used to address thiamine deficiency-related conditions, but it is not a substitute for a balanced diet and a healthy lifestyle. It is always recommended to consult a healthcare professional before starting any new supplements or medications.
Alpha Lipoic Acid: Alpha lipoic acid (ALA) is a naturally occurring antioxidant that is used as a dietary supplement. It plays a vital role in energy metabolism and has been shown to have potential therapeutic effects in various conditions.
One of the primary uses of alpha lipoic acid is in the management of diabetic neuropathy, a type of nerve damage caused by diabetes. ALA has been found to improve symptoms such as numbness, tingling, and burning sensation in the hands and feet associated with this condition.
The exact mechanism of action of alpha lipoic acid is not fully understood, but it is believed to have antioxidant and anti-inflammatory properties. It can help neutralize harmful free radicals in the body and protect against oxidative stress, which is an underlying factor in many chronic diseases.
The recommended dose of alpha lipoic acid for diabetic neuropathy is typically 600-1200 mg per day, divided into two or three doses. It is usually taken orally as a supplement.
Alpha lipoic acid is generally considered safe when used as directed. However, some individuals may experience side effects such as stomach upset, nausea, and skin rash. Rarely, it may cause allergic reactions or low blood sugar levels in people with diabetes.
It’s important to note that alpha lipoic acid may interact with certain medications and supplements, so it’s advisable to consult with a healthcare professional before starting or changing any supplements or medications.
Chromium Picolinate: Chromium Picolinate is a supplement that contains the trace mineral chromium bound to picolinic acid. It is commonly used as a nutritional supplement for its potential beneficial effects on blood sugar control and weight management.
The exact mechanism of action of Chromium Picolinate is not fully understood, but it is believed to enhance the action of insulin, a hormone responsible for regulating blood sugar levels. Insulin helps cells take up glucose from the bloodstream and convert it into energy. Chromium is thought to optimize insulin function by increasing insulin sensitivity, which can lead to improved blood sugar control.
The recommended dose of Chromium Picolinate varies depending on the individual’s age, sex, and specific health condition. However, the typical dosage ranges from 200 to 1000 mcg (micrograms) per day. It is important to follow the instructions on the product label or consult a healthcare professional for personalized dosage recommendations.
While Chromium Picolinate is generally considered safe for most people when taken at recommended doses, it may cause some side effects. Common side effects can include digestive issues such as stomach pain, diarrhea, and nausea. In rare cases, some individuals may experience skin reactions or headaches. It is essential to consult a healthcare professional if any unusual or severe side effects occur.
It is worth noting that Chromium Picolinate should not be used as a sole treatment for diabetes or any other medical condition. It is meant to be used as a supplement alongside a healthy diet and lifestyle to support overall blood sugar control and weight management. It is always recommended to speak with a healthcare professional before starting any new supplement regimen, especially if there are existing health conditions or medication interactions to consider.
Methycobalamin: Methycobalamin is a form of vitamin B12 that is used to treat vitamin B12 deficiency, certain kinds of nerve pain, and to support the functioning of the nervous system. It is available as an injectable solution or as an oral tablet.
The main mechanism of action of Methycobalamin is its ability to serve as a cofactor for enzymes involved in the synthesis of DNA and the metabolism of proteins and fats. Vitamin B12 plays a crucial role in the formation of myelin, a protective layer around nerve fibers. By aiding in the production of myelin, Methycobalamin helps to maintain the health and integrity of the nervous system. It also plays a role in the development and functioning of red blood cells.
The dosing of Methycobalamin can vary depending on the specific condition being treated. For vitamin B12 deficiency, a typical dose may range from 500 mcg to 1000 mcg injected intramuscularly once daily or three times a week for several weeks, followed by a maintenance dose of 1000 mcg given once monthly. For nerve pain, the usual dose is 1500 to 6000 mcg per day in divided doses.
Side effects of Methycobalamin are generally rare but can include mild diarrhea, nausea, and skin rash. In some cases, allergic reactions such as itching, swelling, or dizziness may occur. If any severe side effects are experienced, such as difficulty breathing, chest pain, or abnormal bleeding, immediate medical attention should be sought.
Methycobalamin is generally considered safe for most individuals, but it may interact with certain medications or conditions. It is important to inform your healthcare provider about any other medications, supplements, or medical conditions before starting Methycobalamin. They will be able to determine if Methycobalamin is suitable and safe for your specific situation.
Myo-Inositol: Myo-Inositol is a dietary supplement and a form of inositol, a naturally occurring nutrient found in certain foods and produced in the body. It is often used as a treatment for various conditions, including polycystic ovary syndrome (PCOS), anxiety, depression, and insulin resistance.
The exact mechanism of action of Myo-Inositol is not fully understood, but it is believed to affect various signaling pathways in the body, including insulin signaling and neurotransmitter activity. It is also thought to have antioxidant and anti-inflammatory properties, which may contribute to its therapeutic effects.
For PCOS, the recommended dose of Myo-Inositol is typically around 4 grams per day, although the specific dosage may vary depending on individual needs and the advice of a healthcare provider. It is usually taken in divided doses throughout the day, and it can be taken with or without food.
While Myo-Inositol is generally considered safe and well-tolerated, some individuals may experience mild side effects, including nausea, stomach discomfort, and diarrhea. These side effects are usually temporary and can be minimized by starting with a low dose and gradually increasing it over time.
It is important to note that Myo-Inositol may interact with certain medications or supplements, especially those that affect insulin levels or blood sugar control. Therefore, it is always recommended to consult with a healthcare professional before starting any new supplement or medication.
