LISINOPRIL

LISINOPRIL: Lisinopril is a medication primarily used to treat hypertension (high blood pressure) and heart failure. It is classified as an angiotensin-converting enzyme (ACE) inhibitor.

The mechanism of action of lisinopril involves inhibiting the action of ACE, an enzyme responsible for the conversion of angiotensin I to angiotensin II. Angiotensin II is a hormone that causes blood vessels to constrict, leading to increased blood pressure. By inhibiting ACE, lisinopril helps relax and widen blood vessels, reducing blood pressure.

The usual starting dose for lisinopril in the treatment of hypertension is 10 mg once daily, which can be increased up to 40 mg per day if necessary. For heart failure, the initial dose is usually 2.5 mg once daily, with gradual increases up to a maximum dose of 20 mg per day.

As with any medication, lisinopril may cause side effects. Common side effects include dizziness, headache, cough, low blood pressure, and gastrointestinal symptoms such as nausea and diarrhea. Other less common but potentially serious side effects include angioedema (swelling of the face, throat, or tongue), rash, and kidney problems.

It’s important to note that lisinopril should not be taken during pregnancy as it may harm the fetus. It is also not recommended for people with a history of angioedema or bilateral renal artery stenosis.

Patients should always consult their healthcare provider before starting or adjusting any medication.