MEDROXYPROGESTERONE

MEDROXYPROGESTERONE: Drug: Medroxyprogesterone

Use: Medroxyprogesterone is a synthetic form of the hormone progesterone. It is used for a variety of purposes, including contraception, hormone replacement therapy, and the treatment of certain gynecological conditions. It can also be used to control the menstrual cycle or treat abnormal bleeding.

Mechanism of Action: Medroxyprogesterone works primarily by inhibiting the secretion of the hormones necessary for ovulation, thereby preventing pregnancy. It also changes the lining of the uterus, making it less receptive to a fertilized egg. In hormone replacement therapy, it helps to balance hormone levels in menopausal women.

Dose: The dosage of medroxyprogesterone depends on the specific purpose for which it is being prescribed. For contraception, the usual dose is a 150 mg injection every 3 months. In hormone replacement therapy, the dosage can vary but is typically started at 5 to 10 mg per day for a specific period of time.

Side Effects: Common side effects of medroxyprogesterone include irregular menstrual bleeding, breast tenderness, weight changes, headaches, bloating, and mood changes. Some women may experience a decrease in bone mineral density when using medroxyprogesterone for extended periods. Long-term use has also been associated with an increased risk of cardiovascular events such as heart attack or stroke. It is important to discuss the potential risks and benefits of medroxyprogesterone with a healthcare provider before starting treatment.