MEFENAMIC ACID + PARACETAMOL
Mefenamic Acid: Mefenamic Acid is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain and reduce inflammation. It is categorized as a nonselective cyclooxygenase (COX) inhibitor, meaning that it inhibits the production of prostaglandins, which are responsible for pain, fever, and inflammation.
Mefenamic Acid is primarily used to treat mild to moderate pain associated with conditions such as menstrual cramps (dysmenorrhea), arthritis, and other musculoskeletal disorders. It can also be used to relieve pain following dental procedures.
The drug works by inhibiting the COX enzymes, which decrease the production of prostaglandins. This mechanism of action reduces pain, swelling, and inflammation in the affected area.
The typical recommended dose of Mefenamic Acid for adults is 500 mg initially, followed by 250 mg every 6 hours as needed, with a maximum daily dose of 2,500 mg. It should be taken with food to minimize gastrointestinal side effects.
Common side effects of Mefenamic Acid include nausea, stomach pain, heartburn, diarrhea, drowsiness, headache, and dizziness. These side effects are usually mild and temporary. However, if any severe side effects such as allergic reactions, bleeding/ulceration in the stomach or intestine, or liver damage occur, medical attention should be sought immediately.
It is important to note that Mefenamic Acid should not be used if the patient has a history of allergy or asthma symptoms caused by aspirin or other NSAIDs, as it may cause a severe allergic reaction. It should also be used with caution in patients with a history of gastrointestinal bleeding, ulcers, kidney problems, or heart conditions.
As with any medication, it is essential to consult a healthcare professional before starting or altering the dosage of Mefenamic Acid to ensure it is safe and appropriate for the individual.
Paracetamol: Paracetamol, also known as acetaminophen, is a commonly used over-the-counter medication for the relief of pain and fever. It belongs to the class of drugs called analgesics (pain relievers) and antipyretics (fever reducers).
Paracetamol works by inhibiting the synthesis of prostaglandins, which are chemicals that promote inflammation and transmit pain signals to the brain. By reducing the levels of prostaglandins, Paracetamol helps to relieve pain and reduce fever.
The usual dose of Paracetamol for adults is 325-650 mg every 4-6 hours, not exceeding 4000 mg per day. For children, the dose is based on their weight and should be carefully calculated. It is available in various forms, including tablets, capsules, and liquid suspension, making it easy to administer.
Paracetamol is commonly used to treat mild to moderate pain, such as headaches, toothaches, muscle aches, and menstrual cramps. It is also used to reduce fever associated with infections or other causes.
Although generally considered safe when used as directed, Paracetamol can have some side effects. The most common side effects include nausea, stomach pain, and rash. Rarely, it can cause allergic reactions, liver damage (especially with high doses or prolonged use), and blood disorders.
It is important to follow the recommended dose and not exceed the maximum daily limit to minimize the risk of side effects. It is also advised to avoid alcohol consumption while taking Paracetamol, as it can increase the risk of liver damage.
Paracetamol is widely available without a prescription in many countries and is generally considered safe and effective when used appropriately. However, it is always advisable to consult a healthcare professional if you have any concerns or questions about its use.
