PERAMPANEL

PERAMPANEL: Perampanel is a prescription medication that is used to treat partial-onset seizures in patients with epilepsy. It belongs to a class of drugs known as AMPA receptor antagonists.

The primary mechanism of action of perampanel is to block the activity of AMPA receptors in the brain. AMPA receptors are responsible for the transmission of excitatory signals between nerve cells. By blocking these receptors, perampanel helps to reduce the overactivity of nerve cells, preventing the occurrence of seizures.

The dosage of perampanel varies depending on the individual patient and their specific condition. It is typically started at a low dose and gradually increased to the target dose, as determined by the healthcare provider. The usual recommended starting dose for adults is 2 mg per day, and it can be increased by 2 mg increments at weekly intervals. The target maintenance dose is usually between 8 to 12 mg per day. Adolescents aged 12 to 18 years may require higher doses.

Like most medications, perampanel can cause side effects. Common side effects include dizziness, fatigue, irritability, headache, balance problems, and drowsiness. Some patients may also experience behavioral changes, such as aggression, hostility, and suicidal thoughts. It is important to report any unusual or severe side effects to a healthcare professional.

In summary, perampanel is a medication used to treat partial-onset seizures in individuals with epilepsy. It works by blocking AMPA receptors in the brain to reduce overactivity of nerve cells. The dosage varies depending on the patient, and potential side effects include dizziness, fatigue, and changes in behavior.