PIROXICAM
PIROXICAM: Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and treat various conditions such as arthritis, osteoarthritis, and rheumatoid arthritis. It belongs to the class of oxicams.
The mechanism of action of piroxicam involves inhibiting the production of prostaglandins, which are responsible for pain, inflammation, and fever. Piroxicam works by blocking the enzyme cyclooxygenase (COX), which plays a role in the production of prostaglandins.
The usual oral dosage for piroxicam is 20 mg per day, taken as a single dose or divided into two smaller doses. However, the dosage may vary depending on the condition being treated and the individual patient’s response. It is recommended to start with the lowest effective dose and gradually increase if necessary.
As with any medication, piroxicam may have certain side effects. The common side effects include gastrointestinal issues such as indigestion, heartburn, stomach pain, and diarrhea. Piroxicam may also cause dizziness, headache, skin rash, itching, and fluid retention. More serious side effects, though rare, can include gastrointestinal bleeding, liver or kidney problems, and allergic reactions. It is important to seek medical advice if any severe side effects occur.
Piroxicam should be used with caution in patients with a history of gastrointestinal disorders, kidney or liver disease, and those who are pregnant or breastfeeding. It should be avoided in patients with a known allergy to NSAIDs or a history of asthma attacks or other allergic reactions precipitated by NSAIDs.
It is recommended to follow the prescribed dosage and consult a healthcare professional before starting or stopping piroxicam to ensure proper use and minimize the risk of side effects.