PROPRANOLOL + FLUNARIZINE

Propranolol: Propranolol is a medication that belongs to a class of drugs known as beta blockers. It is primarily used in the treatment of high blood pressure (hypertension), angina (chest pain), and certain heart rhythm disorders. Additionally, it is also prescribed to manage symptoms associated with anxiety and panic disorders.

The mechanism of action of propranolol involves blocking the effects of adrenaline on beta receptors within the heart and blood vessels. By doing so, it helps to reduce heart rate and blood pressure, resulting in better control of cardiovascular symptoms.

The recommended dose of propranolol varies depending on the condition being treated. For hypertension and angina, the initial dose is typically 40 mg taken twice daily. This can be adjusted as needed based on individual response. In the case of anxiety or panic disorders, the usual starting dose is 20 mg to 40 mg taken two to three times daily. Again, the dosage may be adjusted based on the individual’s response.

As with any medication, propranolol can cause side effects. Common side effects include fatigue, cold hands or feet, dizziness, slowed heart rate, and mild gastrointestinal discomfort. More serious side effects are rare but can include shortness of breath, unusual bleeding or bruising, depression, and signs of liver problems such as dark urine or yellowing of the eyes or skin.

It’s important to note that propranolol may interact with other medications, so it is crucial to inform your healthcare provider about all the medications you are taking before starting propranolol. Your doctor will also need to monitor your blood pressure and heart rate regularly while on propranolol treatment.

It is highly recommended to consult a healthcare professional for specific dosing instructions and to discuss potential side effects and drug interactions.

Flunarizine: Flunarizine is a medication primarily used for the prevention and treatment of migraine headaches. It belongs to a class of drugs known as calcium channel blockers, which work by blocking the entry of calcium ions into cells, reducing their excitability and relaxing blood vessels.

The exact mechanism of action of Flunarizine in migraine prevention is not fully understood, but it is believed to work by improving cerebral blood flow and reducing the hyperexcitability of neurons that may contribute to migraine attacks.

The usual recommended dose of Flunarizine for migraine prevention is 5-10 mg per day, taken orally. It is usually started at a lower dose and gradually increased if necessary. However, the actual dosage may vary depending on the individual’s response, the severity of their migraines, and their tolerance to the medication. It is important to follow the prescribed dose given by the healthcare provider.

Like any medication, Flunarizine can cause side effects. Common side effects may include drowsiness, weight gain, depression, movement disorders (such as extrapyramidal symptoms), and gastrointestinal disturbances. Rare but potentially serious side effects may include liver function abnormalities, parkinsonism, and symptoms of depression or mood changes. It is important to consult a healthcare professional if any side effects occur.

It is worth noting that Flunarizine may interact with other medications, so it is crucial to inform healthcare providers about all current medications before starting Flunarizine. It is also not recommended for use in individuals with pre-existing movement disorders, severe liver disease, or those taking certain medications such as antipsychotics.

Overall, Flunarizine is an effective medication for the prevention and treatment of migraines, but its use should be carefully monitored by a healthcare professional due to possible side effects and drug interactions.