SODIUM FEREDETATE
SODIUM FEREDETATE: Sodium feretate, also known as sodium ferric hydroxide EDTA, is a medication used in the treatment of iron overload in the body. Iron overload can occur in conditions such as hereditary hemochromatosis, thalassemia, and transfusion-dependent anemias.
The mechanism of action of sodium feretate involves the chelation of excess iron in the body. It forms a complex with iron, which is then eliminated through urine, resulting in a decrease in iron levels.
The usual dose of sodium feretate is determined based on the patient’s individual iron burden. It is typically administered intravenously once a week. The dosage can range from 500 mg to 1 g, depending on the severity of iron overload.
Like any medication, sodium feretate may cause certain side effects. Common side effects include gastrointestinal symptoms such as nausea, vomiting, abdominal pain, and diarrhea. These side effects are usually mild and transient. A rare but serious side effect is an allergic reaction, which may manifest as hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. If any allergic reaction occurs, it is important to seek immediate medical attention.
It is important to note that sodium feretate should be used under the supervision of a healthcare professional experienced in the management of iron overload disorders. Regular monitoring of iron levels and renal function is necessary during treatment.
