TRIOXSALEN
TRIOXSALEN: Trioxsalen is a medication primarily used in combination with ultraviolet (UV) light therapy to treat specific skin conditions. It belongs to a group of drugs called psoralens, which increase the skin’s sensitivity to UV radiation.
The mechanism of action of Trioxsalen involves binding to the DNA in skin cells and forming crosslinks between DNA strands upon exposure to UVA light. This process prevents the rapid replication of cells, which is beneficial in treating conditions like vitiligo, psoriasis, and cutaneous lymphoma.
Trioxsalen is administered orally, usually in the form of a capsule or solution. The dosage varies depending on the specific condition being treated, as well as the patient’s weight, age, and response to therapy. It is important to follow your doctor’s instructions carefully regarding dosing.
As with any medication, Trioxsalen may cause certain side effects, including nausea, dizziness, headache, itching, and redness of the skin. It is essential to avoid excessive sun exposure for 24 hours after taking Trioxsalen, as it can cause an increased risk of sunburn. Eye protection should also be used during treatment to prevent potential eye damage from UV light.
Rare but severe side effects may include severe sunburn, blistering, or swelling of the skin. If any of these occur, it is crucial to seek medical attention immediately.
It is important to note that Trioxsalen should only be used under the supervision of a healthcare professional, as they will be able to tailor the dosage and duration of treatment to your specific needs and monitor for any potential side effects or complications.