URSODEOXYCHOLIC ACID

URSODEOXYCHOLIC ACID: URSODEOXYCHOLIC ACID is a medication primarily used to dissolve gallstones in patients who do not need or want gallbladder surgery. It is also prescribed to treat certain liver diseases.

The mechanism of action of ursodeoxycholic acid involves several processes. It reduces the amount of cholesterol produced by the liver and decreases the absorption of cholesterol from the intestines. It also modifies the composition of bile, making it less likely to form gallstones. Additionally, ursodeoxycholic acid has anti-inflammatory and immunomodulatory effects that can help protect liver cells.

The dose of ursodeoxycholic acid depends on the condition being treated. For gallstone dissolution, the typical initial dose is 8-10 mg/kg per day, divided into two to three doses. After dissolution of the stones, a lower maintenance dose may be prescribed to prevent the formation of new gallstones. For liver diseases, the dose varies depending on the specific condition and the severity of the disease.

The most common side effects of ursodeoxycholic acid include diarrhea, stomach upset, and nausea. These gastrointestinal side effects usually subside over time or can be managed by taking the medication with food. Rarely, more severe adverse effects such as allergic reactions or liver problems may occur, and immediate medical attention should be sought if these occur.

It is important to note that ursodeoxycholic acid may interact with certain medications (e.g., antacids, cholesterol-lowering drugs, and birth control pills), so it is crucial to inform the healthcare provider about all medications being taken before starting treatment. Pregnant or breastfeeding individuals should also consult with their doctor before taking this medication.