VIT B1 + VIT B6 + FOLIC ACID + ALPHA LIPOIC ACID + MECOBALAMIN
Vit B1: Vitamin B1, also known as thiamine, is a water-soluble vitamin that plays a key role in the metabolism of carbohydrates, proteins, and fats in the body. It is an essential nutrient that cannot be synthesized by the body, therefore it must be obtained through diet or supplementation.
Thiamine is commonly used as a nutritional supplement to treat thiamine deficiency or to prevent complications associated with certain conditions such as alcoholism, malabsorption disorders, and chronic liver disease. It is also used in the treatment of Wernicke-Korsakoff syndrome, a neurological disorder caused by thiamine deficiency.
The mechanism of action of thiamine involves its conversion into an active form called thiamine pyrophosphate (TPP). TPP acts as a cofactor for several enzymes involved in carbohydrate metabolism, such as pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase. These enzymes are necessary for the conversion of glucose into energy in the form of ATP.
The recommended daily dose of thiamine varies depending on the individual’s age, sex, and health condition. For adults, the recommended dietary allowance (RDA) is 1.1 mg for females and 1.2 mg for males. In cases of thiamine deficiency or specific medical conditions, higher doses may be prescribed under the supervision of a healthcare professional.
Thiamine is generally well-tolerated, and there are no known side effects associated with its normal use as a dietary supplement. However, in rare cases, high doses of thiamine administered intravenously may cause allergic reactions, such as itching, rash, or difficulty breathing. These reactions usually occur in individuals with a known hypersensitivity to thiamine or other excipients in the formulation.
It is worth noting that excessive thiamine intake does not result in any significant health benefits, as the body can only absorb a limited amount of thiamine at a time. Therefore, it is recommended to adhere to the recommended daily dose or follow the advice of a healthcare professional when taking thiamine supplements.
Vit B6: Vitamin B6, also known as pyridoxine, is one of the eight B-group vitamins that is essential for the proper functioning of the body. It is water-soluble and cannot be stored in the body, so it needs to be obtained through diet or supplements.
Vitamin B6 plays a crucial role in several bodily functions, including the metabolism of proteins, carbohydrates, and fats. It is involved in neurotransmitter synthesis, such as serotonin and dopamine, which are important for mood regulation. Additionally, it supports immune function and helps in the formation of red blood cells.
The main therapeutic use of vitamin B6 is to treat or prevent vitamin B6 deficiency. It is also used in combination with other vitamins as a dietary supplement for various conditions, such as premenstrual syndrome (PMS), depression, morning sickness during pregnancy, and carpal tunnel syndrome.
The mechanism of action of vitamin B6 involves its conversion into the active form called pyridoxal phosphate (PLP), which acts as a coenzyme in many enzymatic reactions. PLP is involved in amino acid metabolism, particularly in the conversion of tryptophan to serotonin and niacin (vitamin B3).
The recommended daily intake of vitamin B6 varies depending on age, gender, and specific conditions. For adults, the recommended dietary allowance (RDA) is 1.3 to 1.7 mg per day. Higher doses may be recommended for certain medical conditions, under the supervision of a healthcare professional.
While vitamin B6 is generally considered safe, high doses or prolonged use may lead to adverse effects. The most common side effects include nausea, vomiting, stomach pain, loss of appetite, headache, and tingling or numbness in the extremities (peripheral neuropathy). Long-term use of high doses of vitamin B6 can also result in neurological symptoms, such as difficulty walking and sensory deficits.
It is important to consult with a healthcare professional before starting any new medication or supplement, including vitamin B6, to ensure proper dosage and avoid potential interactions with other medications or underlying medical conditions.
Folic Acid: Folic Acid, also known as vitamin B9, is a water-soluble vitamin that is essential for the synthesis and repair of DNA, as well as the production of red blood cells. It is commonly used as a dietary supplement and is also prescribed for certain medical conditions.
Folic Acid plays a key role in cell division and growth, making it important for proper development of the fetus during pregnancy. It is also important for the maintenance of a healthy nervous system and can help prevent certain types of anemia. Additionally, Folic Acid may be beneficial in the treatment of depression and certain cardiovascular diseases.
The exact mechanism of action of Folic Acid involves its conversion to tetrahydrofolate, which is an active form of the vitamin. Tetrahydrofolate acts as a coenzyme in several metabolic reactions, including the synthesis of nucleic acids and certain amino acids.
The recommended dosage of Folic Acid varies depending on the age, sex, and specific medical condition of the individual. For general health maintenance, a daily intake of 400-800 micrograms is typically recommended. Pregnant women may require higher doses, usually around 600-800 micrograms per day.
Folic Acid is generally considered safe when used as directed. However, some individuals may experience side effects such as nausea, bloating, and abdominal cramps. In rare cases, allergic reactions may occur, characterized by rash, itching, or difficulty breathing. It can also interact with certain medications, so it is important to consult with a healthcare professional before starting Folic Acid supplementation.
High doses of Folic Acid should be used with caution in individuals with certain medical conditions, such as epilepsy or kidney disease. Additionally, excessive intake of Folic Acid may mask symptoms of vitamin B12 deficiency, which can lead to neurological damage if left untreated.
Overall, Folic Acid is an important nutrient that plays a vital role in various bodily functions. It is commonly used as a supplement and prescribed for specific medical conditions, but it is important to follow recommended dosages and consult with a healthcare professional if any concerns arise.
Alpha Lipoic Acid: Alpha Lipoic Acid (ALA) is a naturally occurring compound found in the body and also available as a dietary supplement. It functions as a powerful antioxidant, helping to protect cells from damage caused by free radicals. ALA is used for various purposes and has gained attention for its potential health benefits.
One of the primary uses of ALA is in the management of diabetic neuropathy, a type of nerve damage that commonly occurs in individuals with diabetes. It is believed that ALA helps to improve nerve function and reduce symptoms such as pain, tingling, and numbness.
ALA also plays a role in energy metabolism. It helps the body convert glucose into energy, potentially making it beneficial for individuals with conditions related to insulin resistance such as metabolic syndrome and type 2 diabetes. It is thought to enhance glucose uptake by cells and contribute to improved insulin sensitivity.
The usual dose of ALA for diabetic neuropathy is between 600-1800 mg per day, although individual needs may vary. It is usually taken orally, either as a standalone supplement or in combination with other nutrients. It is important to follow the dosing instructions provided by the healthcare provider or as indicated on the product label.
Overall, ALA is considered safe for most individuals when taken orally in appropriate doses. However, like any supplement or medication, it may cause side effects in some people. Common side effects of ALA include gastrointestinal issues such as stomach upset, nausea, and diarrhea. Rashes and allergic reactions may also occur, although these are rare.
In very high doses, ALA may lower blood sugar levels and increase the risk of hypoglycemia. Therefore, caution is advised in individuals taking insulin or other medications to control blood sugar levels. Regular monitoring of blood sugar is recommended when using ALA in these scenarios.
It is worth noting that ALA may interact with certain medications, including thyroid hormone replacement therapy and chemotherapy drugs. As with any supplement, it is important to inform a healthcare professional about all medications being taken to avoid potential interactions or adverse effects.
In conclusion, Alpha Lipoic Acid is a natural compound that acts as an antioxidant and has potential benefits for diabetic neuropathy and metabolic disorders. It is generally safe when used in appropriate doses, but it may cause side effects such as gastrointestinal issues. It is important to consult healthcare professionals before starting any new supplement regimen.
Mecobalamin: Mecobalamin, also known as vitamin B12, is a medication commonly prescribed to treat vitamin B12 deficiency. It is an active form of vitamin B12 that plays a crucial role in the formation of red blood cells, the maintenance of nerve cells, and the synthesis of DNA.
Mecobalamin acts as a coenzyme in various metabolic pathways in the body. It is involved in the conversion of homocysteine to methionine, which is necessary for the production of proteins, DNA, and cell division. Mecobalamin also helps in the production of myelin, which coats and protects nerve fibers.
The standard dose of mecobalamin varies depending on the severity of the deficiency and the individual’s age and health condition. It is usually taken orally as tablets or capsules. The usual adult dose is 1,000 to 2,000 micrograms per day, while the recommended dose for children is typically lower. The medication can also be administered via intramuscular injection in cases where oral supplementation is ineffective.
Side effects of mecobalamin are generally rare, especially when used in appropriate doses. However, some individuals may experience mild side effects such as diarrhea, nausea, or a feeling of swelling or itching. In rare cases, hypersensitivity reactions may occur, which can include symptoms like rash, shortness of breath, or swelling of the face, lips, or tongue. If any severe or persistent side effects are observed, it is advised to seek medical assistance.
Mecobalamin should be used with caution in individuals with Leber’s hereditary optic neuropathy or in those with an allergic reaction to cobalt or cobalamin. It may also interact with certain medications, such as anticonvulsants or medications that lower folic acid levels. It is important to inform your healthcare provider about any existing medical conditions or medications to ensure the safety and effectiveness of mecobalamin treatment.
Overall, Mecobalamin is a medication that is used to treat vitamin B12 deficiency and its associated symptoms. Understanding its use, mechanism of action, dose, and potential side effects can help individuals make informed decisions about its consumption and ensure appropriate treatment.
