ALFACALCIDOL

ALFACALCIDOL: ALFACALCIDOL is a medication that is a synthetic derivative of vitamin D. It is used to treat various conditions related to vitamin D deficiency or impaired calcium metabolism.

Mechanism of action:
ALFACALCIDOL is converted in the body to the active form of vitamin D called calcitriol. Calcitriol acts on the intestines, kidneys, and bones to regulate the absorption, metabolism, and utilization of calcium and phosphate. It helps in maintaining proper levels of these minerals in the body and promotes healthy bone formation.

Use:
ALFACALCIDOL is primarily prescribed for the treatment of certain bone diseases such as osteoporosis, osteomalacia (softening of the bones), and hypoparathyroidism (reduced activity of the parathyroid glands). It can also be used in chronic renal failure patients who have low levels of active vitamin D.

Dose:
The dosing of ALFACALCIDOL may vary depending on the specific condition being treated. The usual starting dose for osteoporosis is 0.25 to 1 microgram per day. For the management of hypoparathyroidism, the initial dosage ranges from 0.5 to 2 micrograms per day. The dose may be adjusted based on individual patient needs.

Side effects:
Common side effects of ALFACALCIDOL may include headache, nausea, vomiting, diarrhea, abdominal pain, and muscle weakness. These side effects are usually mild and may resolve with continued use. In some cases, high doses of ALFACALCIDOL can lead to hypercalcemia (high levels of calcium in the blood), which may cause symptoms like excessive thirst, fatigue, muscle weakness, and confusion. It is essential to monitor calcium levels regularly while using ALFACALCIDOL.

It’s important to note that ALFACALCIDOL should only be used under the supervision of a healthcare professional who will determine the appropriate dosage based on individual needs and monitor any potential side effects.