ALLOPURINOL: ALLOPURINOL is a medication used to treat gout and kidney stones caused by high levels of uric acid in the body. It belongs to a class of drugs known as xanthine oxidase inhibitors.

The primary mechanism of action of ALLOPURINOL is to inhibit the enzyme xanthine oxidase, which is responsible for the conversion of hypoxanthine to xanthine and then to uric acid in the body. By inhibiting this enzyme, ALLOPURINOL reduces the production of uric acid, thereby lowering its levels in the blood and preventing the formation of uric acid crystals that cause gout and kidney stones.

The recommended starting dose of ALLOPURINOL for adults is typically 100 to 200 milligrams per day, which may be adjusted based on the individual’s response. For patients with severe gout or tophi (solid uric acid deposits), higher doses may be necessary. It is important to take ALLOPURINOL with plenty of water and after meals to minimize stomach upset.

As with any medication, ALLOPURINOL can cause side effects. Common side effects include rash, drowsiness, dizziness, diarrhea, and gastrointestinal disturbances. Serious side effects such as allergic reactions, liver problems, and blood disorders are rare but can occur. It is important to seek medical attention if any severe side effects occur.

ALLOPURINOL may also interact with certain drugs, such as azathioprine or mercaptopurine, so it is essential to inform your doctor about any other medications you are taking.

Overall, ALLOPURINOL is an effective medication used to treat gout and kidney stones caused by high levels of uric acid. It works by reducing uric acid production in the body, and while it may have side effects, they are usually well-tolerated. It is crucial to follow the prescribed dose and consult a healthcare professional for any concerns or questions.

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