AMANTADINE
AMANTADINE: AMANTADINE is an antiviral and anti-Parkinson’s disease medication. It is used to prevent or treat influenza A virus infections and to manage the symptoms of Parkinson’s disease.
The mechanism of action of amantadine is not completely understood. However, it is believed to work by inhibiting the replication of the influenza A virus and increasing the release of dopamine in the brain, which helps to improve the symptoms of Parkinson’s disease.
For influenza A virus infections, the typical adult dose of amantadine is 200 mg per day, taken either as a single daily dose or divided into two doses of 100 mg. In children, the dose is based on body weight. It is important to note that amantadine is only effective against influenza A viruses and has no activity against other types of influenza viruses.
For the management of Parkinson’s disease, the typical adult dose of amantadine is 100 mg per day, though it may be increased to 200 mg per day if necessary. The dose may be divided into two equal doses taken in the morning and evening.
Like any medication, amantadine can cause side effects. Common side effects can include nausea, dizziness, constipation, dry mouth, and insomnia. More serious side effects are rare but can include confusion, hallucinations, anxiety, and difficulty urinating. It is important to consult with a healthcare professional if any side effects occur or worsen.
It is worth noting that amantadine should be used with caution in patients with a history of psychiatric disorders, seizure disorders, or kidney disease. It is also not recommended for use during pregnancy unless the potential benefit outweighs the risks.
As always, it is important to follow the prescribed dose and instructions provided by your healthcare professional when using amantadine.