BICALUTAMIDE

BICALUTAMIDE: Bicalutamide is a medication classified as an antiandrogen. It is primarily used in the treatment of prostate cancer.

The mechanism of action of bicalutamide involves blocking the action of androgens (male hormones) by binding to the androgen receptors in the prostate and other tissues. By doing so, it prevents the growth and spread of prostate cancer cells, leading to a reduction in tumor size and alleviation of symptoms.

Bicalutamide is usually taken orally in the form of tablets, typically in a dose of 50 mg once daily. It is commonly prescribed in combination with other prostate cancer treatments such as surgery or radiation therapy.

As with any medication, bicalutamide may cause certain side effects. Common side effects include hot flashes, breast enlargement or tenderness, sexual dysfunction, fatigue, diarrhea, constipation, and nausea. Some individuals may also experience liver function abnormalities, such as elevated liver enzymes, although severe liver toxicity is rare. If any severe side effects occur, such as abdominal pain, yellowing of the skin or eyes, dark urine, or persistent nausea/vomiting, it is important to seek medical attention promptly.

It is worth noting that bicalutamide is only effective in hormone-sensitive prostate cancer, meaning it works best when used alongside other treatments that block the production or action of androgens, such as luteinizing hormone-releasing hormone (LHRH) agonists or antagonists. It is not typically effective as a primary treatment for advanced or metastatic prostate cancer.