BUDESONIDE

BUDESONIDE: Budesonide is a corticosteroid medication that is used to treat various respiratory conditions including asthma and chronic obstructive pulmonary disease (COPD). It is also used to treat inflammatory bowel disease such as Crohn’s disease and ulcerative colitis.

The mechanism of action of budesonide involves its potent anti-inflammatory properties. It binds to glucocorticoid receptors in the cells, which leads to a reduction in the release of inflammatory substances in the body. This helps to alleviate symptoms of respiratory conditions and reduce inflammation in the intestines.

The dose of budesonide can vary depending on the specific condition being treated. For asthma, it is typically administered via inhalation with a recommended starting dose of 200-400 micrograms per day in divided doses. For Crohn’s disease and ulcerative colitis, budesonide is usually taken orally with a recommended dose of 9 mg per day for up to 8 weeks.

Like any medication, budesonide can cause side effects. Common side effects include headache, throat irritation, hoarseness, and a fungal infection in the mouth called oral thrush. These side effects are more common with inhalation therapy. When taken orally, side effects can include upset stomach, nausea, diarrhea, and fatigue. Long-term use of budesonide at high doses may also increase the risk of systemic effects such as adrenal suppression, osteoporosis, and increased susceptibility to infection.

It is important to follow the prescribed dose and consult with a healthcare professional if any concerning side effects occur. Budesonide should not be stopped suddenly without medical advice, as it may lead to worsening of symptoms.