CALCIUM + CHOLECALCIFEROL + VITAMIN K2-7 (MENAQUINONE-7)
Calcium: Calcium is a mineral that is essential for various functions in the body, including the building and maintenance of strong bones and teeth, regulation of muscle contractions, nerve function, blood clotting, and hormone secretion. It can be obtained through dietary sources such as dairy products, leafy greens, and fortified foods, or through calcium supplements.
The primary use of calcium supplementation is to treat or prevent calcium deficiency, which can lead to conditions like osteoporosis, osteopenia, and hypocalcemia. It may also be prescribed to individuals who have an increased need for calcium, such as during pregnancy and breastfeeding.
The mechanism of action of calcium involves its incorporation into bone tissue, contributing to bone mineralization and strength. In cases of calcium deficiency, supplementation helps to restore normal levels of this mineral in the body, maintaining proper functioning of various systems.
The recommended daily intake of calcium varies depending on age, sex, and specific needs. However, the general recommended daily allowance of calcium for healthy adults is around 1000-1300 mg. It is important to note that the body can only absorb a limited amount of calcium at one time, so it’s essential to spread the dosage throughout the day.
Common side effects of calcium supplementation include constipation, bloating, gas, and upset stomach. In some cases, excessive calcium intake can lead to hypercalcemia, which can cause symptoms such as nausea, vomiting, confusion, excessive thirst, frequent urination, and kidney problems. Individuals with conditions such as kidney stones, sarcoidosis, or hyperparathyroidism should use calcium supplements with caution, as it may worsen their condition.
It is important to consult with a healthcare professional before starting calcium supplementation, as they can help determine the appropriate dosage and ensure it does not interact with any medications or medical conditions.
Cholecalciferol: Cholecalciferol, also known as Vitamin D3, is a type of vitamin that plays a crucial role in maintaining the balance of calcium and phosphorus in the body. It is typically used as a dietary supplement to treat or prevent vitamin D deficiency.
The mechanism of action of cholecalciferol involves its conversion into its active form, calcitriol, within the body. Calcitriol then acts on the intestines, kidneys, and bones to help regulate calcium and phosphate levels. Cholecalciferol is also involved in enhancing the absorption of calcium from the gastrointestinal tract.
The recommended dose of cholecalciferol varies depending on the individual’s age, sex, and specific needs. For treating vitamin D deficiency, the typical dosages range from 800-2000 international units (IU) per day. However, the dosages can be higher in severe cases of deficiency. It is important to follow the recommended dosage guidelines provided by a healthcare professional.
Side effects of cholecalciferol are rare when taken in appropriate doses. However, excessive intake or long-term use of high doses may lead to vitamin D toxicity. Symptoms of toxicity can include nausea, vomiting, loss of appetite, excessive thirst, frequent urination, constipation, weakness, and weight loss.
It is also important to note that cholecalciferol may interact with certain medications, such as corticosteroids, antacids, and certain anti-seizure drugs. Additionally, individuals with certain medical conditions, such as hypercalcemia or kidney stones, should exercise caution and consult with a healthcare professional before taking cholecalciferol.
Overall, cholecalciferol is an essential vitamin that helps maintain bone health and plays a vital role in calcium and phosphorus regulation. It is commonly used as a dietary supplement to treat or prevent vitamin D deficiency, but proper dosage and monitoring are important to avoid any potential side effects or interactions.
Vitamin K2-7 (menaquinone-7): Vitamin K2-7 (menaquinone-7) is a type of vitamin K that belongs to the group of menaquinones. It is a fat-soluble vitamin that plays a crucial role in blood clotting and bone metabolism. Unlike vitamin K1, which is mainly found in green leafy vegetables, vitamin K2-7 is synthesized by bacteria and is found in fermented foods and some animal products.
The main use of Vitamin K2-7 is to support bone health by enhancing bone mineralization. It does this by activating osteocalcin, a protein that helps bind calcium to the bones. By promoting calcium deposition in the bones, it helps prevent the risk of osteoporosis and fractures.
The mechanism of action of Vitamin K2-7 involves the activation of specific proteins (osteocalcin and matrix Gla protein) that require vitamin K as a cofactor. Without vitamin K, these proteins cannot function properly, leading to impaired bone mineralization and increased risk of fractures.
The recommended dose of Vitamin K2-7 varies depending on the individual’s age, sex, and specific health conditions. However, a typical daily dose ranges from 45 to 180 micrograms per day. It is available in supplement form and is usually taken orally with a meal to aid in absorption.
Vitamin K2-7 is generally considered safe and well-tolerated when taken within the recommended dose range. However, some individuals may experience minor side effects such as headache, nausea, or an upset stomach. In rare cases, high doses of vitamin K2-7 may lead to an allergic reaction or an adverse effect on blood clotting.
As with any supplement, it is important to consult with a healthcare professional before starting any new medication, especially if you have any underlying medical conditions or are taking other medications that could interact with Vitamin K2-7.
