CARBOXY METHYL CELLULOSE
CARBOXY METHYL CELLULOSE: Carboxy Methyl Cellulose (CMC) is a commonly used drug in the pharmaceutical industry. It is also known by its trade name Sodium Carboxymethyl Cellulose or CMC-Na. CMC is used for its various applications as a pharmaceutical grade excipient, viscosity modifier, stabilizer, tablet binder, and suspending agent in both oral and topical formulations.
Mechanism of Action:
CMC is a water-soluble, linear polysaccharide derived from cellulose. It works by absorbing water and forming a viscous gel or solution, depending on the concentration. This gel-like substance helps to provide lubrication, hydration, and a protective barrier on the surface it is applied to or ingested. In pharmaceutical formulations, CMC exhibits its action by increasing the viscosity of creams, ointments, suspensions, and gels, thereby improving the stability and spreading characteristics of these formulations.
Use and Dose:
CMC is used in various pharmaceutical formulations, including eye drops, artificial tears, lotions, creams, gels, and oral suspensions. It is commonly used as a thickening agent in these preparations to enhance their efficacy and patient compliance. The dose of CMC varies depending on the formulation and the condition being treated. It is important to follow the specific instructions provided by the healthcare professional or the product label.
Side Effects:
CMC is generally considered safe and well-tolerated. However, some individuals may experience mild side effects. These can include temporary eye discomfort or irritation when used in eye drop formulations. In oral formulations, it may cause gastrointestinal symptoms such as bloating, gas, or diarrhea in some individuals. These side effects are usually mild and resolve spontaneously. In rare cases, hypersensitivity reactions can occur, leading to skin rash or itching. If any severe or persistent side effects are experienced, it is important to consult a healthcare professional for further advice.
It is important to note that this description is a general overview of CMC and its use. Different pharmaceutical preparations containing CMC may have specific uses, dosages, and side effects. Therefore, it is best to consult the product literature or a healthcare professional for accurate and detailed information related to a specific CMC formulation.
