CHLOPHENIRAMINE + PHENYLEPHRINE HYDROCHLORIDE
Chlopheniramine: Chlopheniramine is an antihistamine drug used to relieve symptoms of allergic conditions such as hay fever, allergic conjunctivitis, and urticaria (hives). It is also sometimes used for the symptomatic relief of the common cold.
The mechanism of action of Chlopheniramine involves blocking the effects of histamine, a substance released by the body during an allergic reaction. By blocking histamine receptors, Chlopheniramine helps to alleviate symptoms such as itching, sneezing, runny nose, and watery eyes.
The dose of Chlopheniramine varies depending on the age and condition being treated. In adults, the typical oral dose is 4 mg every 4 to 6 hours, not exceeding 24 mg in 24 hours. In children 12 years and older, the recommended dose is 2-4mg every 4-6 hours. Children 6-12 years old usually take 1-2mg every 4-6 hours. It is important to follow the prescribed dose and duration as directed by a healthcare professional.
Common side effects of Chlopheniramine may include drowsiness, dizziness, dry mouth, blurred vision, constipation, and urinary retention. These side effects are generally mild, but if they become severe or persistent, it is important to seek medical attention.
Chlopheniramine can interact with other medications, including sedatives, tranquilizers, other antihistamines, and certain antidepressants. It is important to inform your healthcare provider of all medications you are taking to avoid potential interactions.
Chlopheniramine is available both over-the-counter and with a prescription. It is important to read and follow the label instructions or follow the guidance of a healthcare professional when taking this medication.
Phenylephrine Hydrochloride: Phenylephrine Hydrochloride is a medication commonly used as a nasal decongestant, in eye drops to dilate the pupil, and as a vasoconstrictor in cases of low blood pressure.
The mechanism of action of Phenylephrine Hydrochloride is by stimulating alpha-adrenergic receptors present in the smooth muscles of blood vessels. This stimulation causes constriction of the blood vessels, leading to a reduction in congestion in the nasal passages, dilation of the pupils, and an increase in blood pressure.
The usual oral dose of Phenylephrine Hydrochloride for nasal congestion is 10 mg every four hours, not to exceed 60 mg daily. For eye drops, it is typically used in concentrations of 2.5% to 10%. The dosage for low blood pressure is determined based on the individual patient’s needs.
Common side effects of Phenylephrine Hydrochloride include increased blood pressure, headaches, dizziness, nausea, and anxiety. It may also cause difficulty in sleeping, irritability, and tremors. If taken in excessive amounts, it can lead to more serious side effects such as heart palpitations, chest pain, and shortness of breath.
It is important to consult a healthcare professional before using Phenylephrine Hydrochloride, especially for individuals with underlying medical conditions such as hypertension, diabetes, or cardiovascular disease. Phenylephrine Hydrochloride is also contraindicated in patients taking certain medications such as monoamine oxidase inhibitors (MAOIs) and beta blockers.
