D-PANTHENOL + THIAMINE + VITAMIN B3 (NIACINAMIDE) + MEHTYL COBALAMINE + PYRIDOXINE (VITAMIN B6)
D-Panthenol: Drug Name: D-Panthenol
Use: D-Panthenol is a provitamin form of vitamin B5 (pantothenic acid) that is used as a medication to treat various skin conditions. It is commonly used topically to promote wound healing, prevent and treat burns, and moisturize and soothe dry or irritated skin. Additionally, it is also used in hair care products to strengthen and improve the condition of hair.
Mechanism of Action: D-Panthenol is converted into pantothenic acid in the body, which is an essential component of coenzyme A. Coenzyme A is involved in various metabolic processes, including the synthesis of fatty acids, cholesterol, and certain neurotransmitters. D-Panthenol is thought to act as a moisturizer and promotes healing by enhancing the skin’s barrier function, reducing water loss, and stimulating cell proliferation.
Dose: D-Panthenol is available in various formulations, including creams, ointments, lotions, gels, and shampoos. The specific dose and frequency of application will depend on the formulation and the condition being treated. It is important to follow the instructions provided by your healthcare professional or the product label.
Side Effects: D-Panthenol is generally considered safe and well-tolerated when used topically. Common side effects may include mild skin irritation or redness at the application site. Allergic reactions to D-Panthenol are rare but possible. If you experience any severe or persistent side effects, it is important to seek medical attention.
It is always recommended to consult with a healthcare professional or pharmacist before using D-Panthenol to ensure its suitability for your specific condition and to address any potential interactions or contraindications.
Thiamine: Thiamine, also known as vitamin B1, is a water-soluble vitamin commonly used as a dietary supplement. It plays a crucial role in the body’s energy production and is essential for the proper functioning of the nervous system, heart, muscles, and other organs.
Thiamine is primarily used to treat or prevent thiamine deficiency, which can occur due to inadequate dietary intake, malnutrition, alcoholism, or certain medical conditions that impair absorption. Thiamine deficiency can lead to a serious condition called beriberi, characterized by symptoms like weakness, fatigue, nerve damage, and cardiovascular problems.
The mechanism of action of thiamine involves its conversion into its active form, thiamine pyrophosphate (TPP). TPP acts as a coenzyme in multiple enzyme reactions, particularly those involved in the metabolism of carbohydrates, amino acids, and fatty acids. By participating in these reactions, thiamine helps convert food into energy, assists in nerve conduction, and plays a role in DNA and RNA synthesis.
Thiamine is available in various forms, including oral tablets, capsules, and injections. The recommended daily intake for adults is usually around 1.1 to 1.4 mg, although specific doses may vary depending on age, gender, and individual needs. In medical conditions such as thiamine deficiency or alcohol withdrawal, higher doses may be prescribed by a healthcare professional.
Thiamine is generally considered safe and well-tolerated when used at recommended doses. However, some individuals may experience mild side effects like stomach upset, nausea, headache, or allergic reactions. High doses of thiamine may rarely cause anaphylaxis, a severe allergic reaction. It is important to consult a healthcare professional before starting thiamine supplementation, especially if you have any pre-existing medical conditions or are taking other medications.
Overall, thiamine is an important nutrient that helps maintain the proper functioning of various body systems. It is commonly used to treat thiamine deficiency and associated conditions, and its safety profile is generally favorable when used at recommended doses.
Vitamin B3 (niacinamide): Vitamin B3, also known as niacinamide, is a form of vitamin B3 that is used as a dietary supplement. It is essential for the proper functioning of the body and plays a crucial role in various metabolic processes.
Its primary use is to treat and prevent niacin deficiency, a condition that can lead to a range of symptoms including fatigue, pellagra, skin disorders, and digestive issues. Additionally, niacinamide is sometimes prescribed in higher doses as a medication to manage certain medical conditions, such as high cholesterol levels and diabetes.
The mechanism of action for niacinamide involves its conversion into coenzymes called nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). These coenzymes play a vital role in cellular metabolism, including the breakdown of carbohydrates, fats, and proteins for energy production. They also participate in DNA repair, cell signaling, and regulation of gene expression.
The recommended daily dose of niacinamide for adults is usually between 14-18 mg for men and 12-14 mg for women. However, higher doses may be prescribed by a healthcare professional for specific medical conditions. It is important to follow the dosage instructions provided by your healthcare provider or the product label.
Niacinamide is generally considered safe when used as a dietary supplement, but higher doses can cause some side effects. The most common side effects include flushing, itching, and tingling of the skin, often referred to as the “niacin flush.” This side effect is harmless but can be uncomfortable. Using an extended-release form of niacinamide or taking the supplement with food may help reduce the incidence of flushing.
In rare cases, high doses of niacinamide can cause more serious side effects such as liver damage, gastrointestinal issues, and elevated blood sugar levels. Therefore, it is essential to consult with a healthcare professional before taking higher doses of niacinamide as a medication.
It is worth noting that niacinamide may interact with certain medications, such as blood thinners and diabetes medications. It is important to inform your healthcare provider about all the medications and supplements you are taking to prevent any potential interactions.
Overall, niacinamide (Vitamin B3) is a crucial nutrient that plays a vital role in the body’s metabolic processes. Whether used as a dietary supplement or as a medication for specific medical conditions, it should be used under the guidance of a healthcare professional to ensure proper dosage and monitoring of potential side effects.
Mehtyl Cobalamine: Methyl Cobalamin is a form of Vitamin B12 that is used as a dietary supplement. It plays a vital role in the formation of red blood cells, DNA synthesis, and nerve function. Methyl Cobalamin is commonly prescribed to treat vitamin B12 deficiency, which can occur due to poor absorption, certain medical conditions, or a vegan/vegetarian diet.
The mechanism of action of Methyl Cobalamin involves its conversion into coenzyme B12 which is necessary for the conversion of homocysteine to methionine. It also participates in the synthesis of myelin, the substance that protects nerve fibers.
The recommended dose of Methyl Cobalamin varies depending on the individual’s age, sex, and specific medical condition. It is typically administered orally, as a sublingual tablet, or through injections. The prescribed dosage may range from 1000-5000 mcg per day, depending on the severity of the vitamin B12 deficiency and the physician’s recommendation.
Common side effects of Methyl Cobalamin are usually mild and can include nausea, diarrhea, headache, and dizziness. In rare cases, allergic reactions may occur, which can cause itching, swelling, or difficulty breathing. If any severe side effects or allergic reactions are experienced, medical attention should be sought immediately.
It is important for individuals taking Methyl Cobalamin to follow the prescribed dosage and consult their healthcare provider if they have any pre-existing medical conditions or are taking other medications. Vitamin B12 supplements, including Methyl Cobalamin, are generally safe and well-tolerated when used appropriately.
Pyridoxine (vitamin B6): Pyridoxine, also known as vitamin B6, is a water-soluble vitamin that is essential for various bodily functions. It is generally available over-the-counter and can be found in both food sources and supplement form. Here is some information about pyridoxine:
Use: Pyridoxine is commonly prescribed to treat or prevent vitamin B6 deficiency. It is also used in certain medical conditions where there is a deficiency or increased requirement of vitamin B6, such as certain types of anemia, neurologic conditions, and pregnancy-induced nausea and vomiting.
Mechanism of Action: Pyridoxine plays a crucial role in the metabolism of various amino acids, glucose, and lipids. It acts as a coenzyme for over 100 enzymatic reactions involved in protein metabolism, neurotransmitter synthesis, and hemoglobin formation. By participating in these reactions, pyridoxine supports the functioning of the nervous system, immune system, and helps regulate hormone levels.
Dose: The recommended daily dosage of pyridoxine varies based on age, sex, and specific medical conditions. For adults, the typical oral dose ranges from 1.3 to 1.7 milligrams per day. However, higher doses may be prescribed in certain cases under a healthcare professional’s supervision.
Side Effects: Pyridoxine is generally safe when taken within the recommended dosage range. However, high doses (typically above 200 mg per day) or long-term use may lead to vitamin B6 toxicity. Common side effects include mild gastrointestinal symptoms such as nausea, vomiting, abdominal pain, and diarrhea. In rare cases, prolonged use of high doses may result in nerve damage, leading to sensory impairments. It is important to follow the recommended dosage and consult a healthcare professional if any persistent or severe side effects occur.
It is worth noting that as with any medication or supplement, it is essential to consult a healthcare professional before starting pyridoxine or any other vitamin or medication, especially if you have pre-existing medical conditions or are taking other medications.
