DABIGATRAN ETEXILATE
DABIGATRAN ETEXILATE: Dabigatran etexilate is a prescription medication used to reduce the risk of stroke and blood clots in people with atrial fibrillation (a type of irregular heartbeat) not caused by a heart valve problem. It is also used to treat and prevent blood clots in the veins of the legs (deep vein thrombosis) and in the lungs (pulmonary embolism).
Mechanism of Action:
Dabigatran etexilate belongs to a class of drugs called direct oral anticoagulants. It works by inhibiting a substance in the blood called thrombin. Thrombin is responsible for the formation of blood clots, so by inhibiting its activity, dabigatran etexilate helps to prevent clot formation.
Dose:
The recommended dose of dabigatran etexilate for atrial fibrillation is typically 150 mg taken orally twice daily. For the treatment and prevention of blood clots in the veins, the usual dose is 150 mg taken orally twice daily after initial treatment with a parenteral anticoagulant for at least five days.
Side Effects:
Common side effects of dabigatran etexilate may include digestive symptoms like upset stomach, indigestion, or diarrhea. Other common side effects include minor bleeding, such as nosebleeds, gum bleeding, or bruising. In rare cases, dabigatran etexilate can cause serious bleeding, which may require medical intervention. Other rare but serious side effects include allergic reactions, liver problems, or jaundice.
It is important to note that dabigatran etexilate may interact with other medications, so it is crucial to inform the healthcare provider about all current medications, including over-the-counter drugs and supplements, before starting treatment. Regular monitoring of kidney function is also necessary while taking this medication.
This is not an exhaustive list of side effects, and it is important to consult with a healthcare professional for more information about the risks and benefits of dabigatran etexilate.