DITHRANOL
DITHRANOL: Drug Name: Dithranol
Use: Dithranol is a topical medication used to treat psoriasis, a chronic skin condition characterized by red, scaly patches. It can also be used for other skin disorders such as seborrheic dermatitis and eczema.
Mechanism of Action: The exact mechanism of dithranol in treating psoriasis is not fully understood. However, it is thought to work by reducing the rapid growth of skin cells and dampening the immune response in the affected area. Dithranol has anti-inflammatory effects and helps to normalize the abnormal skin cell proliferation in psoriatic plaques.
Dose: Dithranol is available in various formulations such as creams, ointments, and pastes. The concentration of dithranol also varies depending on the severity of the condition. Typically, a low concentration (0.1-1%) is used initially, and the strength may be gradually increased if necessary. The application is usually done once daily, and the duration of treatment varies depending on the individual’s response and the severity of the condition.
Important note: The exact dose and duration of treatment should be determined by a healthcare professional, as it may vary for each individual.
Side Effects: Dithranol is generally well-tolerated, but it can cause some side effects. Common side effects include skin irritation, itching, burning sensation, redness, or dryness at the application site. These side effects are usually mild and temporary. However, if they persist or worsen, it is important to seek medical advice.
Less common, but more severe side effects include an allergic reaction (rash, itching, swelling, severe dizziness, trouble breathing), skin discoloration, or the development of new skin lesions. If any of these side effects occur, it is crucial to stop using dithranol immediately and consult a healthcare professional.
It is worth noting that dithranol stains clothing, skin, and hair. Therefore, it is recommended to protect clothing and bedding during application and to thoroughly wash hands after use.
As always, it is important to disclose any other medications, supplements, or medical conditions to your healthcare professional before starting dithranol treatment to ensure its safety and effectiveness.
