FOLIC ACID + BENFOTIAMINE + ALPHA LIPOIC ACID + MECOBALAMIN + PYRIDOXINE HYDROCHLORIDE + CHROMIUM POLYNICOTINATE + MYO-INOSITOL
Folic Acid: Folic Acid is a synthetic form of the B-vitamin folate. It plays a crucial role in the production and maintenance of DNA, as well as the formation of red blood cells. It is commonly used as a dietary supplement to treat or prevent folate deficiency, which can occur due to inadequate intake, poor absorption, or certain medical conditions.
The mechanism of action of Folic Acid involves its conversion into active forms of folate, which are essential for various biological processes. It serves as a coenzyme in the synthesis of purines and pyrimidines, the building blocks of DNA and RNA. Folic Acid also contributes to the methylation of DNA, which plays a role in gene regulation and cellular function.
The usual recommended dose of Folic Acid for adults is 400-800 micrograms per day. However, the specific dosage may vary depending on the individual’s needs and the reason for supplementation. It can be taken orally with or without food, as directed by a healthcare professional.
Folic Acid is generally well-tolerated, and side effects are rare at the recommended doses. However, some individuals may experience mild side effects such as nausea, bloating, gas, or a bitter taste in the mouth. Rarely, allergic reactions may occur, characterized by itching, swelling, or difficulty breathing. If any severe or persistent side effects occur, medical attention should be sought immediately.
It is important to note that Folic Acid supplementation is crucial during pregnancy to prevent neural tube defects in the developing fetus. Pregnant women are typically advised to take higher doses of Folic Acid, usually prescribed by their healthcare providers.
Additionally, individuals taking certain medications, such as methotrexate or phenytoin, may require higher doses of Folic Acid to counteract the drug’s effects on folate metabolism. It is recommended to consult with a healthcare professional before starting Folic Acid supplementation, particularly if you have any underlying medical conditions or are taking other medications.
Benfotiamine: Benfotiamine is a synthetic derivative of thiamine (vitamin B1). It is primarily used as a dietary supplement to treat or prevent thiamine deficiency, particularly in individuals with alcoholism, malabsorption issues, or those following a diet deficient in thiamine.
The mechanism of action of benfotiamine involves its conversion into thiamine in the body. Thiamine is an essential nutrient that plays a crucial role in various metabolic processes, including the production of energy from carbohydrates, amino acid metabolism, and nerve function. By increasing thiamine levels, benfotiamine helps support these vital processes.
The recommended dose of benfotiamine varies depending on the specific condition being treated. For general thiamine deficiency, a typical dose is 300 mg to 600 mg per day in divided doses. However, for diabetic neuropathy, higher doses of up to 1200 mg per day may be required. It is always advisable to follow the instructions provided by the healthcare professional or the product label.
Benfotiamine is generally well-tolerated, and side effects are rare. However, some individuals may experience mild gastrointestinal symptoms such as nausea, vomiting, or diarrhea. Allergic reactions are also possible but quite uncommon.
It is worth noting that while benfotiamine has been studied for various conditions, including diabetes, neuropathy, and kidney disease, the evidence for its effectiveness in these areas is limited. As with any dietary supplement, it is important to consult with a healthcare professional before starting benfotiamine or making any changes to your current medication regimen.
Alpha Lipoic Acid: Alpha lipoic acid (ALA) is a naturally occurring compound that functions as a coenzyme in various metabolic processes. It is found in foods such as spinach, broccoli, and organ meats. ALA is also available as a dietary supplement.
USE:
ALA is primarily used as a treatment for diabetic neuropathy, a complication of diabetes that causes nerve damage leading to pain, numbness, and tingling in the hands and feet. It has also been studied for its potential benefits in various other conditions, including antioxidant support, weight loss, and improving skin health.
MECHANISM OF ACTION:
ALA acts as an antioxidant, protecting cells from oxidative damage caused by free radicals. It can regenerate other antioxidants like vitamins C and E, and it also has anti-inflammatory properties. ALA has been shown to enhance glucose utilization and improve insulin sensitivity, which may be beneficial in managing diabetes.
DOSE:
For diabetic neuropathy, the usual recommended dose of ALA is 600-1800 mg per day. It is typically taken orally, and the dosage may vary depending on individual needs and the severity of the condition. It is important to follow the instructions provided by your healthcare professional or the product label when taking ALA.
SIDE EFFECTS:
ALA is generally well-tolerated, and most people experience minimal side effects, if any. Some possible side effects that have been reported include gastrointestinal disturbances (nausea, stomach discomfort), skin rash, and dizziness. These side effects are usually mild and transient. ALA may also interact with certain medications, so it is advisable to consult with a healthcare professional before starting ALA supplementation.
As with any dietary supplement, it is important to purchase ALA from reputable sources to ensure product quality and purity. It is also crucial to inform your healthcare provider about any other medications or supplements you are taking, as they may interact with ALA.
Mecobalamin: Mecobalamin, also known as methylcobalamin, is a form of the vitamin B12. It is an essential nutrient that plays a crucial role in the formation of red blood cells, DNA synthesis, and neurological function.
Mecobalamin is mainly used in the treatment of vitamin B12 deficiency, which can lead to anemia and neurological disorders. It is also prescribed for conditions like pernicious anemia, diabetic neuropathy, and as a supplement for vegetarians and vegans who may have insufficient dietary intake of vitamin B12.
The mechanism of action of Mecobalamin involves its conversion into active coenzymes that participate in various metabolic reactions. It acts as a cofactor for methionine synthase, an enzyme involved in the synthesis of methionine from homocysteine. This process helps in the production of myelin, the protective covering of nerve fibers, and the maintenance of a healthy nervous system.
The usual recommended dose of Mecobalamin varies depending on the condition being treated. For vitamin B12 deficiency, the typical adult dose is 1000-1500 mcg IM (intramuscular) or sublingually (under the tongue) daily for 1-2 weeks, followed by a maintenance dose of 100-1000 mcg monthly. For diabetic neuropathy, the usual dose is 1500 mcg IM daily for 2 weeks, then 1000 mcg IM weekly for 4 weeks, followed by a maintenance dose of 1000 mcg monthly.
Common side effects of Mecobalamin are generally rare and include headache, nausea, and diarrhea. Allergic reactions may occur in some individuals, resulting in symptoms such as itching, rash, swelling, or difficulty breathing. In very rare cases, Mecobalamin may cause hypokalemia or pain at the injection site. It is important to consult a healthcare professional if any unusual or severe side effects are experienced while taking this medication.
Please note that this information is only a general overview and should not substitute proper medical advice. It is essential to consult a healthcare professional before starting or changing any medication regimen.
Pyridoxine Hydrochloride: Pyridoxine Hydrochloride, commonly known as vitamin B6, is a water-soluble vitamin and a form of pyridoxine that is used as a dietary supplement. It is essential for the body’s metabolism, particularly in the synthesis of neurotransmitters, amino acids, and hemoglobin.
Pyridoxine Hydrochloride is used to treat and prevent vitamin B6 deficiency, which can occur due to poor diet, malabsorption disorders, or certain medical conditions. It is also utilized in the treatment of certain neurological conditions, including peripheral neuropathy and premenstrual syndrome (PMS).
The mechanism of action of Pyridoxine Hydrochloride involves its conversion to its active form, pyridoxal phosphate, which acts as a cofactor for many enzymatic reactions involved in protein, carbohydrate, and lipid metabolism. It plays a crucial role in the synthesis of neurotransmitters such as serotonin, dopamine, and gamma-aminobutyric acid (GABA).
The recommended dose of Pyridoxine Hydrochloride varies depending on the individual’s age, sex, and medical condition. For adults, the typical daily dosage ranges from 1.3 to 2.0 mg, while children require lower doses depending on their age. It is available in oral tablet or capsule forms and is usually taken with food to enhance absorption.
While Pyridoxine Hydrochloride is generally safe when taken within the recommended dosage, some individuals may experience mild side effects such as nausea, vomiting, stomach pain, headache, and drowsiness. In rare cases, high doses of pyridoxine (above 2000 mg per day) may lead to more severe neurological side effects, including peripheral neuropathy, numbness, and tingling in the extremities.
It is important to note that Pyridoxine Hydrochloride may interact with certain medications, such as anticonvulsants, levodopa, and some antibiotics. Therefore, it is essential to consult with a healthcare provider or pharmacist before starting or changing the dosage of this medication.
Overall, Pyridoxine Hydrochloride is an essential vitamin supplement that helps maintain the proper functioning of various physiological processes in the body. It should be used under medical guidance and supervision to ensure safe and effective use.
Chromium Polynicotinate: Chromium Polynicotinate is a supplement that combines the mineral chromium with niacin, also known as vitamin B3. It is often used as a nutritional supplement to support healthy blood sugar levels and promote weight loss.
The mechanism of action of Chromium Polynicotinate is not fully understood, but it is believed to enhance the action of insulin, a hormone that helps regulate blood sugar. Insulin helps transport glucose from the bloodstream into cells, where it can be used for energy. Chromium may also play a role in regulating carbohydrate and lipid metabolism.
The recommended dose of Chromium Polynicotinate varies depending on the individual’s needs and the specific product being used. It is commonly available in dosages ranging from 200 to 1000 micrograms (mcg), and is usually taken once daily with meals.
Chromium Polynicotinate is generally considered safe when taken at recommended doses. However, some individuals may experience side effects such as stomach irritation, headaches, or dizziness. Large doses of chromium should be avoided as they can cause toxicity symptoms such as kidney damage, liver problems, and low blood sugar levels.
It is important to note that while Chromium Polynicotinate may be beneficial for some individuals, it is not a substitute for a balanced diet and healthy lifestyle. It is always recommended to consult with a healthcare professional before starting any new supplement regimen. They can help determine if Chromium Polynicotinate is appropriate for your specific health needs and can advise on the optimal dosage.
Myo-Inositol: Myo-Inositol is a naturally occurring substance that belongs to the B-vitamin family. It plays a crucial role in various cellular functions in the body, including cell signaling, insulin sensitivity, and lipid metabolism. As a supplement, Myo-Inositol is mainly used for its potential therapeutic effects in certain medical conditions, such as polycystic ovary syndrome (PCOS) and anxiety disorders.
In PCOS, Myo-Inositol has been shown to help regulate hormone levels, improve insulin sensitivity, reduce insulin resistance, and promote regular ovulation. It is often used as a complementary treatment alongside lifestyle changes and other medications to manage PCOS symptoms, such as irregular periods, infertility, and excessive hair growth.
The exact mechanism of action of Myo-Inositol is not fully understood. However, it is believed to work by regulating the insulin signaling pathway, which subsequently affects the production and release of hormones involved in PCOS. Myo-Inositol may also have a direct impact on ovarian function and follicular development.
The recommended dose of Myo-Inositol varies depending on the condition being treated. For PCOS, the typical dose ranges from 1,200 mg to 4,000 mg per day, which is usually divided into two or three doses. It is recommended to start with a lower dose and gradually increase it if needed. It is important to follow the instructions provided by a healthcare professional or the product packaging.
Myo-Inositol is generally well-tolerated, and side effects are rare. However, some individuals may experience mild gastrointestinal symptoms, such as nausea, diarrhea, or bloating. These side effects are usually temporary and resolve on their own. It is important to consult a healthcare professional before starting Myo-Inositol, especially if you have any pre-existing medical conditions or are taking other medications.
Overall, Myo-Inositol is considered a safe and potentially beneficial supplement for individuals with PCOS or certain anxiety disorders. However, it is always recommended to consult a healthcare professional before starting any new medication or supplement.
