FOLIC ACID + PYRIDOXINE (VITAMIN B6) + METHYL COBALAMIN
Folic Acid: Folic Acid, also known as vitamin B9, is a water-soluble vitamin that is essential for the proper functioning of the body. It is commonly used as a dietary supplement and is also prescribed in higher doses for medical conditions that result in folate deficiency.
Folic Acid plays a crucial role in the synthesis and repair of DNA, as well as in cell division and growth. It is particularly important for the development and maintenance of a healthy nervous system, and it is crucial during pregnancy to ensure proper fetal development and reduce the risk of birth defects such as neural tube defects.
The recommended daily dose of Folic Acid for adults is 400-800 micrograms. Pregnant women are advised to take 600-800 micrograms per day. Higher doses may be prescribed for specific medical conditions under the guidance of a healthcare professional.
There are generally no significant side effects associated with the use of Folic Acid when taken at recommended doses. However, some individuals may experience mild side effects such as nausea, loss of appetite, and abdominal bloating. This is more commonly observed when high doses are taken. Very high doses of Folic Acid can mask the symptoms of vitamin B12 deficiency, which can lead to irreversible nerve damage if left untreated.
It is important to note that Folic Acid supplements should not replace a balanced diet but rather complement it. It can be found naturally in many foods such as leafy green vegetables, fruits, beans, and fortified cereals. Pregnant women and individuals with specific medical conditions should consult with their healthcare professional to determine the appropriate dosage and duration of Folic Acid supplementation.
Pyridoxine (vitamin B6): Pyridoxine, also known as vitamin B6, is a water-soluble vitamin that is necessary for various bodily functions. It is commonly used as a supplement to treat or prevent vitamin B6 deficiency and associated conditions.
The main mechanism of action of pyridoxine is its involvement in the metabolism of proteins, carbohydrates, and fats. It acts as a coenzyme in various enzymatic reactions, helping in the conversion of amino acids, synthesis of neurotransmitters such as serotonin and dopamine, and the formation of heme (a component of hemoglobin).
Pyridoxine is available in various forms including oral tablets, capsules, and injections. The recommended daily dose for adults is around 1.3-1.7 mg, although it may vary depending on age, gender, and specific conditions being treated. Higher doses may be prescribed for individuals with certain medical conditions, such as peripheral neuropathy or certain types of anemia.
While pyridoxine is generally considered safe, excessive consumption of vitamin B6 can lead to toxicity symptoms such as numbness, tingling, and nerve damage. High doses exceeding the upper limit of daily intake (UL) of 100 mg can result in peripheral neuropathy characterized by sensory disturbances. Long-term use of high doses may also have adverse effects on nerve function, sensory neuropathy, and even skin lesions.
Interactions with certain medications, such as antiepileptic drugs and levodopa (used in Parkinson’s disease), may occur, potentially interfering with their efficacy or causing unwanted side effects. It is important to consult a healthcare professional before starting or changing the dosage of pyridoxine, especially if taking other medications.
Overall, pyridoxine is an essential nutrient that plays a vital role in various bodily functions. However, it is important to use it under the supervision of a healthcare professional and adhere to recommended dosage guidelines to prevent adverse effects.
Methyl Cobalamin: Methyl Cobalamin, also known as Methylcobalamin or Vitamin B12, is a form of the essential water-soluble vitamin B12. It is commonly used as a dietary supplement and as a treatment for vitamin B12 deficiency.
The primary function of Methyl Cobalamin is to support the normal functioning of the nervous system and the formation of red blood cells. It is also involved in the synthesis of DNA and plays a vital role in maintaining the health of nerve cells.
When taken orally or administered through injections, Methyl Cobalamin is converted into methylcobalamin in the body. Methylcobalamin acts as a cofactor for the enzyme methionine synthase, which helps in the conversion of homocysteine to methionine. This conversion is necessary to produce essential building blocks for proteins and DNA in the body.
The dose of Methyl Cobalamin depends on the individual’s age, the severity of the deficiency, and the underlying health condition. Generally, oral supplementation ranges between 500 to 1,000 mcg per day, while injections are typically given at a dose of 1,000 to 5,000 mcg.
Common side effects of Methyl Cobalamin are rare but can include:
1. Mild diarrhea or upset stomach
2. Allergic reactions, such as itching, rash, or swelling
3. Headache or dizziness
4. Nausea or vomiting
It is important to note that Methyl Cobalamin may interact with certain medications, so individuals should consult their healthcare provider before starting any new supplements. Furthermore, long-term and excessive use of Methyl Cobalamin without medical supervision may result in high levels of vitamin B12 in the body, potentially causing complications.
Overall, Methyl Cobalamin is a safe and effective treatment for vitamin B12 deficiency when used as directed. It is essential to follow the recommended dosage and consult a healthcare professional for personalized advice.
