LUBIPROSTONE SOFT GELATIN

LUBIPROSTONE SOFT GELATIN: Lubiprostone soft gelatin is a medication used for the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation in adults. It is marketed under the brand name Amitiza.

The mechanism of action of lubiprostone involves activating chloride channels in the gastrointestinal (GI) tract. This helps to increase fluid secretion into the intestines, which facilitates the passage of stool and relieves constipation. It also helps to decrease pain and bloating associated with irritable bowel syndrome.

The recommended dose of lubiprostone for chronic idiopathic constipation is 24 micrograms twice daily. For irritable bowel syndrome with constipation, the recommended dose is 8 micrograms twice daily. The capsules should be taken with food and swallowed whole, without chewing or crushing.

Like any medication, lubiprostone may cause side effects. The most common side effects include nausea, diarrhea, abdominal pain, flatulence, headache, and vomiting. These side effects are usually mild to moderate in severity and may improve with continued use. If these side effects persist or become severe, it is advisable to consult a healthcare professional.

It is important to note that lubiprostone should not be used in patients with a history of mechanical gastrointestinal obstruction. It is also not recommended for use during pregnancy as its safety has not been established in pregnant women. Therefore, it is essential to consult a healthcare professional before starting lubiprostone soft gelatin to discuss the potential risks and benefits in individual cases.