LURASIDONE
LURASIDONE: Lurasidone is an atypical antipsychotic drug used for the treatment of schizophrenia and depressive episodes associated with bipolar I disorder (bipolar depression) in adults. It is sold under the brand name Latuda.
The exact mechanism of action of lurasidone is not fully understood, but it is believed to work by blocking the activity of certain neurotransmitters in the brain, specifically dopamine D2 and serotonin 5-HT2A receptors. By antagonizing these receptors, lurasidone helps to restore the balance of neurotransmitters in the brain, which can alleviate symptoms of schizophrenia and bipolar depression.
The initial recommended dose of lurasidone for schizophrenia is 40 mg/day, taken orally with food. Depending on individual patient response, the dose can be increased up to a maximum of 160 mg/day. For the treatment of bipolar depression, the starting dose is also 40 mg/day, but it can be increased to a maximum of 120 mg/day.
Common side effects of lurasidone include drowsiness, restlessness, nausea, vomiting, constipation, and weight gain. It may also cause movement disorders such as tremor, stiffness, and uncontrollable movements. Some less common but potentially serious side effects include neuroleptic malignant syndrome (a rare but potentially fatal reaction to antipsychotic medication), tardive dyskinesia (involuntary movements), and metabolic changes (such as increased blood sugar, cholesterol, and triglyceride levels). It is important to report any unusual or severe side effects to a healthcare professional.
Lurasidone may also interact with other medications or medical conditions, so it is important to inform your healthcare provider about any other medications or health conditions you may have before starting treatment. Additionally, lurasidone may cause sedation, so it is advisable to avoid driving or operating heavy machinery until you are familiar with how the medication affects you.
Overall, lurasidone is a commonly prescribed medication for schizophrenia and bipolar depression, and its effectiveness and tolerability may vary depending on individual patients’ needs and circumstances. It is important to follow dosage instructions and communicate any concerns or questions to a healthcare professional.
