MEGESTROL ACETATE

MEGESTROL ACETATE: Drug: MEGESTROL ACETATE

Use: Megestrol acetate is a synthetic progestin hormone that is used for various medical conditions. It may be prescribed to treat advanced breast or endometrial cancer, as well as to stimulate appetite and weight gain in patients with cancer or HIV/AIDS. It is also sometimes used as a contraceptive.

Mechanism of Action: Megestrol acetate works by binding to progesterone receptors in the body. This leads to changes in the lining of the uterus, inhibition of ovulation, and alterations in the cervical mucus, making it difficult for sperm to pass through. In patients with cancer, it may help to slow down the growth of tumor cells.

Dose: The prescribed dose of megestrol acetate will vary depending on the condition being treated. For appetite stimulation and weight gain in patients with cancer or HIV/AIDS, the usual dose is 400-800 mg per day. For the treatment of advanced breast or endometrial cancer, the recommended dose is typically 160-320 mg per day. It is important to follow the dosage instructions provided by the healthcare provider.

Side Effects: Common side effects of megestrol acetate may include increased appetite, weight gain, fluid retention, dizziness, headache, hot flashes, menstrual changes, and changes in libido. Some individuals may also experience gastrointestinal symptoms such as nausea, vomiting, and diarrhea. Less common but more serious side effects may include blood clots, liver problems, and allergic reactions. It is essential to notify a healthcare professional if any severe side effects or allergic reactions occur.

It is worth noting that megestrol acetate should not be used during pregnancy as it may cause harm to the unborn baby. It may also interact with certain medications, so it is important to inform the healthcare provider about all current medications and medical conditions beforehand.