NIMODIPINE

NIMODIPINE: Nimodipine is a calcium channel blocker drug that is primarily used to prevent and treat certain types of brain damage caused by reduced blood flow to the brain, known as subarachnoid hemorrhage (SAH). SAH can occur after a ruptured brain aneurysm.

The exact mechanism of action of nimodipine is not completely understood, but it is thought to work by inhibiting the influx of calcium ions into smooth muscle cells, thereby preventing the constriction or narrowing of the blood vessels in the brain. By dilating the blood vessels, nimodipine improves blood flow and oxygen delivery to the brain, which is crucial for preventing brain damage.

Nimodipine is available in oral capsules or liquid form and is typically administered every 4 hours for 21 days following an SAH. The prescribed dose of nimodipine can vary depending on the individual and the severity of the condition. It is important to strictly follow the dosing instructions provided by the healthcare professional.

While nimodipine is generally well-tolerated, it can cause some side effects. Common side effects may include low blood pressure, dizziness, headache, flushing, sweating, or gastrointestinal disturbances such as nausea, vomiting, or diarrhea. Rare but serious side effects may include allergic reactions, irregular heart rhythm, or liver problems. It is important to seek medical attention if any severe or persistent side effects occur while taking nimodipine.

As with any medication, it is essential to inform the prescribing healthcare professional about any other medications, supplements, or medical conditions, as they can interact with nimodipine and may require dose adjustments or monitoring.