NOT AVAILABLE + CHOLECALCITEROL.
Not Available: I apologize, but I cannot provide information on a drug called ‘Not Available’ as it does not exist. If you have any other specific drug in mind, please let me know and I’ll be happy to assist you.
Cholecalciterol.: Drug: Cholecalciferol
Use: Cholecalciferol, also known as Vitamin D3, is a dietary supplement used to treat and prevent Vitamin D deficiency. It helps the body absorb calcium and phosphorus, necessary for maintaining healthy bones and teeth. Cholecalciferol is also prescribed for certain medical conditions such as osteoporosis, hypoparathyroidism, and renal osteodystrophy.
Mechanism of Action: Cholecalciferol is a prohormone that undergoes metabolism in the liver and kidneys to form the active hormone, calcitriol. Calcitriol regulates the levels of calcium and phosphate in the body, promoting their absorption from the intestine, reabsorption in the kidneys, and mobilization from bones.
Dose: The recommended dosage of cholecalciferol can vary depending on the indication and individual needs. For Vitamin D deficiency, the typical dose is 1000-2000 international units (IU) per day. However, in certain medical conditions, higher doses may be required, and a doctor should determine the appropriate dosage for each patient.
Side Effects: Most people tolerate cholecalciferol well and experience minimal side effects. However, high doses or long-term use may lead to certain adverse effects, including:
1. Hypercalcemia: Excessive calcium levels in the blood, resulting in symptoms such as nausea, vomiting, constipation, bone pain, and increased thirst.
2. Kidney damage: Prolonged excessive doses can potentially damage the kidneys.
3. Hypercalciuria: Increased calcium levels in urine, which can lead to the formation of kidney stones.
4. Hypervitaminosis D: Rare but can occur with extremely high doses, resulting in symptoms like weakness, headache, loss of appetite, weight loss, and irregular heart rhythm.
It is important to follow the recommended dosage and consult a healthcare professional before starting cholecalciferol to ensure it is safe and appropriate for your specific needs and medical condition.
