ROSUVASTATIN

ROSUVASTATIN: ROSUVASTATIN, sold under the brand name Crestor, is a medication commonly used to lower cholesterol levels in the blood. It belongs to a group of drugs called statins, which work by inhibiting an enzyme called HMG-CoA reductase. This enzyme is responsible for the production of cholesterol in the liver.

The primary use of rosuvastatin is to treat hypercholesterolemia, specifically high levels of low-density lipoprotein cholesterol (LDL-C), also known as “bad” cholesterol. By lowering LDL-C levels, rosuvastatin helps reduce the risk of cardiovascular events such as heart attacks, strokes, and angina.

The recommended starting dose of rosuvastatin is typically 5 to 10 mg per day, taken orally. The dosage can be adjusted based on the patient’s response and lipid profile. Maximum daily dosages are generally 40 mg for patients without predisposing factors and 20 mg for patients at higher risk.

Common side effects of rosuvastatin include headache, muscle pain, abdominal pain, nausea, constipation, and diarrhea. These symptoms are usually mild and temporary. In rare cases, more serious side effects can occur, such as liver problems, muscle breakdown (rhabdomyolysis), and an increased risk of diabetes. Patients taking rosuvastatin should be monitored regularly for liver function and muscle-related symptoms.

It is important to note that rosuvastatin, like other statins, can interact with other medications. It may increase the risk of side effects when taken with certain drugs, such as fibrates, certain antibiotics, and some antifungals. Additionally, grapefruit and grapefruit juice should be avoided while taking rosuvastatin, as they can increase the levels of the drug in the blood.

Overall, rosuvastatin is an effective medication for managing high cholesterol levels and reducing the risk of cardiovascular events. However, it should only be used under the supervision of a healthcare professional and in combination with a healthy lifestyle, including a balanced diet and regular exercise.