SENNA GLYCOSIDES

SENNA GLYCOSIDES: Drug Name: Senna Glycosides

Use: Senna glycosides are primarily used as a laxative to treat constipation. They are particularly effective in cases where increased bowel movement is required, such as before a surgical procedure or diagnostic tests like colonoscopy.

Mechanism of Action: Senna glycosides are natural compounds found in the leaves and pods of the Senna plant. Within the body, they are transformed into active metabolites known as rhein anthrones. These metabolites stimulate the intestinal muscles, promoting peristalsis and enhancing the movement of fecal matter through the colon. This results in increased bowel movements and softening of the stool.

Dose: The recommended dose of senna glycosides may vary depending on the formulation and individual patient factors. It is essential to follow the instructions provided by the healthcare professional or the package insert. Generally, senna glycosides are taken orally as tablets, capsules, or liquid. A common starting dose for adults is 15-30 mg taken before bedtime. The maximum daily dose should not exceed 60 mg. For children, the dose will depend on their age and weight, and a pediatrician’s guidance should be sought.

Side Effects: Senna glycosides are generally well-tolerated, but like any medication, they can cause side effects. The most common side effects include abdominal cramps, diarrhea, nausea, and electrolyte imbalances. Prolonged or excessive use of senna glycosides may result in dependence or reduced colon function. In rare cases, individuals may experience an allergic reaction to senna glycosides, characterized by symptoms like rash, itching, swelling, severe dizziness, or difficulty breathing. If any side effects occur, it is important to consult a healthcare professional.