TENOFOVIR

TENOFOVIR: Tenofovir is an antiviral drug used primarily in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It is available in different formulations such as tablets, oral powder, and intravenous solution.

The primary mechanism of action of Tenofovir is inhibition of the viral reverse transcriptase enzyme. This enzyme is responsible for the replication of the HIV and HBV viruses by converting viral RNA into DNA. By inhibiting this enzyme, Tenofovir prevents the replication of the virus and slows down the progression of the infection.

Tenofovir is usually taken once daily with or without food. The recommended dose varies depending on the specific formulation and the condition being treated. For HIV infection, the recommended dose is usually 300mg once daily. For HBV infection, the recommended dose is 300mg once daily for adults and 6mg/kg once daily for pediatric patients.

While Tenofovir is generally well-tolerated, it can cause some side effects. Common side effects include nausea, vomiting, diarrhea, headache, dizziness, fatigue, and abnormal kidney function. In some cases, it may also cause bone loss or renal toxicity, though these side effects are relatively rare.

It is important for patients taking Tenofovir to have regular monitoring of kidney function and bone density. Some individuals may require dosage adjustments or more frequent monitoring based on their specific health conditions.

Overall, Tenofovir is an effective antiviral medication used to manage HIV and HBV infections. However, it is essential to follow the prescribed dosage and undergo regular monitoring to ensure its safe and effective use.