VILDAGLIPTIN + REMOGLIFLOZIN
Vildagliptin: Vildagliptin is an oral antidiabetic drug used to treat type 2 diabetes. It belongs to the class of medications known as dipeptidyl peptidase-4 (DPP-4) inhibitors.
The primary mechanism of action of Vildagliptin is inhibiting the activity of DPP-4 enzyme, which is responsible for the degradation of the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). By inhibiting DPP-4, Vildagliptin increases the levels of GLP-1 and GIP, which in turn stimulates the release of insulin from pancreatic beta cells in response to elevated blood sugar. Additionally, it suppresses the release of glucagon, which reduces blood glucose levels further.
The dosage of Vildagliptin usually ranges from 50 mg to 100 mg per day, typically taken orally once or twice daily, either with or without food. The actual dose depends on the individual’s response and the recommendations of a healthcare professional.
As with any medication, Vildagliptin may have side effects. Common side effects include headache, dizziness, nasopharyngitis (inflammation of the nose and pharynx), upper respiratory tract infection, and gastrointestinal symptoms like nausea, diarrhea, and abdominal pain. In rare cases, it may cause severe skin reactions, pancreatitis, or liver problems. It is important to consult a healthcare provider if any side effects occur or worsen.
Remogliflozin: Remogliflozin is a drug used to treat type 2 diabetes mellitus. It belongs to a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors.
The mechanism of action of Remogliflozin involves blocking the SGLT2 protein in the kidneys. By inhibiting this protein, Remogliflozin reduces the reabsorption of glucose from the urine back into the bloodstream. As a result, more glucose is excreted through the urine, which lowers blood sugar levels.
The recommended dose of Remogliflozin depends on the individual patient and their specific needs. It is typically taken orally once daily in the morning before breakfast. The dosage may be adjusted by a healthcare professional based on the patient’s response to the medication and other factors.
Like any medication, Remogliflozin can cause side effects. Common side effects may include urinary tract infections (UTIs), increased urination, genital yeast infections, thirst, increased cholesterol levels, and changes in uric acid levels. These side effects are usually mild and resolve on their own. However, it is important to notify a healthcare professional if any side effects persist or worsen.
In rare cases, Remogliflozin can cause more serious side effects such as kidney problems, dehydration, low blood pressure, ketoacidosis (a serious condition where the body produces high levels of ketones), and hypersensitivity reactions. If any of these severe side effects occur, immediate medical attention should be sought.
As with any medication, it is important to follow the prescribed dosage and instructions provided by a healthcare professional when taking Remogliflozin. Regular monitoring of blood sugar levels and kidney function may also be necessary during treatment with this medication.
