VITAMIN B3 (NIACINAMIDE) + FOLIC ACID + LACTOBACILLUS
Vitamin B3 (niacinamide): Vitamin B3, also known as niacinamide, is a water-soluble vitamin that plays a crucial role in the body’s energy metabolism. It is commonly used as a dietary supplement and is also found naturally in various foods.
Niacinamide has multiple therapeutic uses due to its involvement in various metabolic processes. It is primarily used to treat niacin deficiency and associated conditions like pellagra. Additionally, it is used in the management of high cholesterol levels, triglycerides, and cardiovascular diseases. Niacinamide also has some benefits for skin health and is used topically to treat acne, rosacea, and other dermatological conditions.
The exact mechanism of action of niacinamide is not fully understood. However, it is converted in the body into nicotinamide adenine dinucleotide (NAD+), a coenzyme involved in numerous biochemical reactions. NAD+ plays a vital role in energy production and cellular metabolism. It also functions as a cofactor for enzymes involved in DNA repair and maintains the integrity of the cellular genome. Additionally, niacinamide has anti-inflammatory properties.
The dosage of niacinamide can vary depending on the condition being treated and the individual. For the treatment of pellagra or niacin deficiency, the recommended daily dose is usually around 500-1000 mg per day. When used for cholesterol management, doses of 1000-2000 mg per day may be prescribed. Topical niacinamide formulations for skin conditions can range from 2-5% concentration applied twice daily.
Niacinamide is generally considered safe when taken within the recommended dosage range. However, higher doses may cause side effects such as flushing, itching, and gastrointestinal upset. These side effects are more common with immediate-release forms of niacin and may be minimized with extended-release formulations or by taking the medication with food. It is important to note that niacinamide does not typically cause the niacin-induced flushing seen with higher doses of niacin.
In rare cases, high-dose niacinamide supplements can lead to liver toxicity, so regular liver function monitoring is recommended during prolonged usage. Individuals with liver disease, stomach ulcers, or gout should use niacinamide with caution and under medical supervision.
As with any medication or supplement, it is recommended to consult a healthcare professional before starting niacinamide to ensure appropriate dosage and to identify potential drug interactions or contraindications.
Folic Acid: Folic acid, also known as folate, is a type of vitamin B9 that functions as an essential nutrient for the body. It is used as a dietary supplement to treat or prevent certain deficiencies that arise due to poor diet, pregnancy, alcoholism, liver disease, and other medical conditions.
Folic acid is required for the production and maintenance of new cells, including the synthesis of DNA and RNA. It plays a crucial role in the development of red blood cells and helps prevent the occurrence of anemia. Additionally, it is vital for proper brain function and is used in the treatment of certain mental health disorders.
The recommended dose of folic acid depends on the individual’s age, sex, and specific medical condition. For most adults, 400-800 micrograms per day is considered an appropriate dosage. During pregnancy, the dosage may increase to 600-800 micrograms per day. It is important to follow the recommended dosage as excessive intake of folic acid can be harmful.
While folic acid is generally safe for consumption, it can cause some side effects. These can include digestive problems such as nausea, bloating, gas, and a bitter taste in the mouth. In rare cases, it may cause allergic reactions characterized by itching, rash, or difficulty breathing. If any severe side effects arise, medical attention should be sought immediately.
Folic acid may interact with certain medications, such as methotrexate and certain anticonvulsants, so it is important to inform your healthcare provider about all the medications you are taking before starting folic acid supplementation.
Overall, folic acid is an essential nutrient that is used to treat or prevent deficiencies and assist in the proper functioning and development of cells in the body. It is important to follow dosage instructions and consult a healthcare provider if any adverse effects are experienced.
Lactobacillus: Lactobacillus is a type of bacterium that is commonly found in the human body, especially in the gastrointestinal tract. It is considered a probiotic and is used as a dietary supplement to restore and maintain the natural balance of bacteria in the gut.
Mechanism of Action:
Lactobacillus works by colonizing the intestines and producing lactic acid, which creates an acidic environment. This acidic environment helps inhibit the growth of harmful bacteria and promotes the growth of beneficial bacteria. It also helps to maintain a healthy balance of microorganisms in the gut, which aids digestion and boosts the immune system.
Use:
Lactobacillus is commonly used to treat various gastrointestinal conditions such as diarrhea, irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD). It can also be used to prevent or treat vaginal infections and urinary tract infections. Additionally, lactobacillus is sometimes used to improve digestion and overall gut health.
Dose:
The recommended dosage of lactobacillus can vary depending on the specific product and the condition being treated. It is available in several forms, including capsules, tablets, powders, and liquids. The dosage instructions provided on the product label should be followed. It is generally recommended to take lactobacillus with meals to maximize its effectiveness.
Side Effects:
Lactobacillus is generally considered safe for most people. However, some individuals may experience mild side effects such as bloating, gas, and an upset stomach. These side effects are usually temporary and subside on their own. It is rare, but some people may experience more severe allergic reactions or infections from consuming lactobacillus products. If any unusual or severe side effects occur, it is important to discontinue use and consult a healthcare professional.
It is worth noting that different strains of lactobacillus may have varying effects and effectiveness for different conditions. Therefore, it is recommended to speak with a healthcare provider before starting any new supplement regimen to ensure it is appropriate for your specific needs.
