VITAMIN B3 (NIACINAMIDE) + RIBOFLAVINE + ASCORBIC ACID + PYRIDOXINE HCL + D-PANTHENOL + THIAMINE MONONITRATE
Vitamin B3 (niacinamide): Vitamin B3, also known as niacinamide, is a water-soluble vitamin that plays an essential role in various metabolic processes in the body. It is commonly used as a dietary supplement to treat and prevent niacin deficiency and related conditions.
The primary mechanism of action of niacinamide is its conversion into its active form, nicotinamide adenine dinucleotide (NAD+), which is involved in many enzymatic reactions in cellular metabolism. NAD+ is essential for energy production, DNA repair, and cellular communication.
Niacinamide is often prescribed to manage certain medical conditions such as pellagra, a deficiency disease caused by inadequate dietary intake of niacin or tryptophan. It is also used to treat hyperlipidemia (high cholesterol and triglycerides) and some types of acne. Additionally, niacinamide is sometimes used as an adjunctive treatment in osteoarthritis and inflammatory skin conditions like acne vulgaris and rosacea.
The recommended dose of niacinamide depends on the individual’s age, underlying condition, and specific requirements. For treating niacin deficiency, doses typically range from 10 to 100 mg per day. Higher doses, ranging from 500 to 2000 mg per day, are often used for the management of hyperlipidemia. However, it is crucial to follow the dosage instructions provided by a healthcare professional.
Niacinamide is generally well-tolerated, but some people may experience mild side effects, including flushing, itching, headache, dizziness, and gastrointestinal symptoms such as nausea and vomiting. These side effects are more common with higher doses or immediate-release formulations. Extended-release formulations may minimize flushing but can still cause potential gastrointestinal side effects.
In rare cases, high doses of niacinamide may lead to liver toxicity, so regular monitoring of liver function is recommended for individuals taking long-term high-dose niacinamide therapy.
It is important to consult a healthcare professional before starting niacinamide supplementation, especially if you have any pre-existing medical conditions or are taking other medications, as it may interact with certain drugs including blood thinners, diabetes medications, and medications metabolized by the liver.
Overall, niacinamide is a valuable nutrient with a range of uses, helping support overall health and wellbeing. However, it is essential to use it under the guidance of a healthcare professional to ensure safety and efficacy.
Riboflavine: Riboflavine, also known as Vitamin B2, is a water-soluble vitamin that plays a crucial role in energy metabolism. It is commonly used as a supplement to treat or prevent riboflavin deficiency.
The main function of riboflavin is to act as a coenzyme in various biochemical reactions in the body, particularly those involved in the metabolism of carbohydrates, fats, and proteins. It also acts as an antioxidant, helping to protect cells from oxidative stress.
Riboflavin is typically available as an oral supplement in tablet or capsule form. The recommended daily dose for adults is 1.3 mg for men and 1.1 mg for women. However, higher doses may be prescribed for individuals with specific conditions or deficiencies.
As a vitamin, riboflavin is generally well-tolerated and has a low risk of side effects. The most common side effect is harmless yellowish discoloration of urine. In rare cases, higher doses may cause diarrhea or an increase in urine frequency. Allergic reactions are extremely rare.
It is important to note that riboflavin should not be used as a substitute for a balanced diet. It is best to obtain vitamin B2 from natural food sources such as dairy products, eggs, lean meats, green leafy vegetables, and whole grains.
Overall, riboflavine is an essential vitamin that is important for maintaining good health and preventing deficiencies. It is generally safe, but it is always advisable to consult with a healthcare professional before starting any new supplements or making changes to your diet.
Ascorbic Acid: Ascorbic Acid, also known as Vitamin C, is a water-soluble vitamin that is naturally present in food and is also available as a dietary supplement. It is used to prevent or treat low levels of vitamin C in the body, which may occur due to a poor diet or certain health conditions.
The main function of ascorbic acid is as an antioxidant, which means it helps protect cells from damage caused by free radicals. Free radicals are compounds that are formed in the body during normal metabolic processes and can also be produced by exposure to environmental factors like pollution and cigarette smoke. By neutralizing these free radicals, ascorbic acid helps reduce oxidative stress and inflammation in the body.
The recommended daily intake of ascorbic acid varies depending on factors such as age, sex, and overall health. For adults, the recommended dietary allowance is 75-90 mg per day for women and 90-120 mg per day for men. Higher doses may be recommended in certain situations, such as during pregnancy or if you have a deficiency.
While ascorbic acid is generally considered safe at recommended doses, high doses can cause side effects such as stomach upset, diarrhea, and nausea. In some people, large doses of ascorbic acid may increase the risk of kidney stones. Individuals with certain medical conditions, such as kidney disease or a history of kidney stones, should consult with a healthcare professional before taking high doses of ascorbic acid.
It is important to note that ascorbic acid should not be used as a replacement for a balanced diet, and the best way to meet your vitamin C needs is through a healthy and varied diet. Sources of ascorbic acid include citrus fruits, strawberries, kiwi, broccoli, bell peppers, and tomatoes. If you are considering taking ascorbic acid supplements, it is advisable to consult with a healthcare professional to determine the right dosage and to ensure it does not interact with any other medications you may be taking.
Pyridoxine Hcl: Pyridoxine HCl, also known as vitamin B6, is a water-soluble vitamin that plays a crucial role in various physiological processes in the body. It is mainly used as a dietary supplement to prevent or treat vitamin B6 deficiency.
The primary mechanism of action of Pyridoxine HCl is its conversion into its active form, pyridoxal 5′-phosphate (PLP). PLP serves as a coenzyme in over 100 enzymatic reactions involved in amino acid metabolism, neurotransmitter synthesis, and glycogen breakdown.
Pyridoxine HCl is available in various formulations, including oral tablets and capsules. The dosage depends on the individual’s age, sex, and medical condition. The recommended daily dose for adults is usually between 1.3-1.7 mg, while pregnant and lactating women may require a slightly higher dose.
Most people tolerate Pyridoxine HCl well and rarely experience side effects. However, some individuals may encounter adverse reactions such as mild gastrointestinal symptoms (nausea, vomiting, abdominal pain), headache, or drowsiness. These side effects are usually transient and resolve with continued use.
It’s important to note that high doses of Pyridoxine HCl (more than 200 mg per day) over a prolonged period may lead to vitamin B6 toxicity. Symptoms of toxicity can include sensory neuropathy, numbness, and difficulty walking. Therefore, it is essential to follow the recommended dosage and consult a healthcare professional before initiating any supplementation.
D-Panthenol: D-Panthenol, also known as pro-vitamin B5 or dexpanthenol, is a synthetic derivative of pantothenic acid (vitamin B5). It is primarily used as a moisturizer and skin conditioning agent in various cosmetics, skincare products, and pharmaceutical preparations.
Mechanism of Action:
When applied topically, D-Panthenol is converted into pantothenic acid, which is an essential component of coenzyme A. Coenzyme A plays a critical role in many metabolic processes, including the synthesis of fatty acids and the production of energy from carbohydrates, proteins, and fats. D-Panthenol promotes hydration and helps improve the skin’s barrier function. It also has anti-inflammatory properties and can accelerate wound healing.
Use:
D-Panthenol is commonly used in skincare products to moisturize and soothe dry, rough, or irritated skin. It can be found in various forms, such as creams, lotions, ointments, and gels. D-Panthenol is also used in hair care products to enhance hair elasticity, strength, and shine.
Dose:
The dosage of D-Panthenol varies depending on the formulation and the specific product being used. It is typically applied topically to the affected area as per the instructions provided by the manufacturer. It is important to follow the recommended dosage and application method.
Side Effects:
D-Panthenol is generally considered safe and well-tolerated when used as directed. It is a non-irritating and non-sensitizing substance, making it suitable for most individuals, including those with sensitive skin. However, like any topical product, there is a minimal risk of allergic reactions or skin irritation. If any adverse reactions occur, such as redness, itching, or rash, it is recommended to discontinue use and consult a medical professional.
It is essential to note that D-Panthenol is intended for external use only and should not be ingested. If accidentally ingested or used improperly, it is advisable to seek medical assistance immediately.
As with any medication or skincare product, it is best to consult a healthcare professional or pharmacist before using D-Panthenol to ensure it is appropriate for your specific needs and to avoid any potential drug interactions or contraindications.
Thiamine Mononitrate: Thiamine Mononitrate is a synthetic form of vitamin B1, also known as thiamine. It is used as a dietary supplement to treat or prevent thiamine deficiency and related conditions.
Thiamine is an essential vitamin that plays a crucial role in converting food into energy. It is also important for the proper functioning of the nervous system and maintaining a healthy cardiovascular system.
The mechanism of action of Thiamine Mononitrate involves its conversion into thiamine pyrophosphate (TPP), the active form of vitamin B1. TPP acts as a cofactor for several enzymes involved in energy metabolism, including those responsible for the breakdown of carbohydrates and amino acids.
Thiamine Mononitrate is available in oral tablet or capsule form. The typical recommended daily dose for adults is around 1.5 to 5 mg, although this may vary based on individual needs and the specific condition being treated. It is usually taken once daily with or without food.
While Thiamine Mononitrate is generally considered safe when used as directed, it may cause certain side effects. Common side effects may include stomach upset, diarrhea, nausea, or an allergic reaction. Rarely, high doses of thiamine supplementation may lead to an allergic or anaphylactic reaction, which requires immediate medical attention.
It is important to note that Thiamine Mononitrate should only be used under the guidance of a healthcare professional, as excessive doses may cause thiamine toxicity. Additionally, certain medical conditions or medications may interact with thiamine supplementation, so it is crucial to consult a healthcare provider before starting or altering the dosage of this medication.
