ZINC + LIGNOCAINE + PHENYLEPHRINE + HYDROCORTISONE + CALCIUM DOBESILATE + LIDOCAINE (LIGNOCAINE OR XYLOCAINE) + TROXERUTIN

Zinc: Zinc is a mineral that is essential for many physiological processes in the body. It is commonly used as a dietary supplement and is also found in various foods.

Use: Zinc is primarily used to help boost the immune system and prevent or treat zinc deficiency. It is often taken to shorten the duration of the common cold, and it may also help with wound healing, acne, age-related macular degeneration, and diarrhea in children.

Mechanism of Action: Zinc plays a crucial role in the functioning of enzymes, which are essential for numerous biochemical reactions in the body. It is involved in immune system function, DNA synthesis, protein synthesis, wound healing, and cell division.

Dose: The recommended daily intake of zinc varies depending on age, sex, and specific needs. Generally, the recommended daily allowance (RDA) for zinc is 11 mg for males and 8 mg for females. Higher doses may be recommended for certain conditions or under the guidance of a healthcare professional. It is commonly available in tablet or capsule form, often as zinc gluconate or zinc sulfate.

Side Effects: When taken in appropriate doses, zinc is generally considered safe for most people. However, excessive intake of zinc can lead to toxicity and adverse effects. Common side effects of zinc supplementation include nausea, vomiting, diarrhea, stomach cramps, and headaches. Prolonged, high-dose use may also lead to copper deficiency. It is important to follow recommended dosages and consult a healthcare professional before starting any supplementation.

Lignocaine: Lignocaine, also known as Lidocaine, is a medication commonly used as a local anesthetic. It is often used to numb a specific area of the body during medical procedures, such as dental work or minor surgeries.

The mechanism of action of Lignocaine involves blocking the transmission of nerve signals in the area where it is applied. It does this by inhibiting the voltage-gated sodium channels, preventing the influx of sodium ions into the nerves and ultimately reducing their ability to transmit pain signals.

Lignocaine is available in various forms including injections, creams, gels, and sprays. The specific dose and route of administration depend on the location and type of procedure being performed. For example, injections are commonly used for dental procedures, while creams or sprays may be used for surface anesthesia.

Like all medications, Lignocaine can have some side effects. Common side effects include temporary numbness or tingling at the site of application, dizziness, drowsiness, and a metallic taste in the mouth. These side effects are usually mild and temporary. In rare cases, allergic reactions can occur, characterized by rash, itching, difficulty breathing, or swelling of the face, lips, tongue, or throat. If any of these serious side effects occur, medical attention should be sought immediately.

It is essential to use Lignocaine as directed by a healthcare professional and to inform them of any underlying medical conditions or medications being taken, as certain interactions or contraindications may exist.

Phenylephrine: Phenylephrine is a medication primarily used as a decongestant to relieve nasal congestion caused by allergies, colds, or sinus infections. It is also used to treat low blood pressure and as a mydriatic (pupil dilator) during eye exams.

Phenylephrine acts by constricting blood vessels in the nasal passages, relieving congestion and improving airflow. It works by selectively activating the alpha-1 adrenergic receptors, leading to vasoconstriction and reducing blood flow in nasal tissues. This action helps decrease the swelling of nasal membranes, allowing for easier breathing.

The drug is available in various formulations, including nasal sprays, oral tablets, liquid solutions, and eye drops. The dose and route of administration depend on the specific formulation and the condition being treated.

For nasal congestion, the recommended dose of phenylephrine nasal spray is usually 1 to 2 sprays in each nostril every 4 hours, not exceeding 3 days of continuous use. The oral tablets or liquid solutions are typically taken every 4 to 6 hours, with a maximum daily dose of 60 mg for adults.

Common side effects of phenylephrine may include increased blood pressure, headache, dizziness, nervousness, nausea, and sleep disturbances. Extended or excessive use of nasal sprays containing phenylephrine can also result in rebound congestion when discontinued. It is important to follow the instructions and not exceed the recommended dose or duration of use to minimize the risk of side effects.

Phenylephrine may not be suitable for individuals with certain medical conditions, such as high blood pressure, heart disease, diabetes, thyroid problems, or prostate issues. It is always advisable to consult a healthcare professional before starting any new medication to determine the appropriate use and dosage based on individual circumstances.

Hydrocortisone: Hydrocortisone is a medication that belongs to the class of corticosteroids. It is a synthetic form of the hormone cortisol, which is produced naturally by the adrenal glands. Hydrocortisone is available in various forms, including creams, ointments, solutions, suppositories, and injections.

Hydrocortisone is used to treat a variety of conditions, including inflammation, allergies, asthma, eczema, psoriasis, and certain autoimmune disorders. It helps to reduce redness, itching, swelling, and other allergic reactions in the body.

The mechanism of action of hydrocortisone involves binding to specific receptors in the cells, known as glucocorticoid receptors. This binding triggers a series of cellular processes that suppress the immune response and reduce inflammation. Additionally, hydrocortisone affects the metabolism of carbohydrates, proteins, and fats in the body.

The dose of hydrocortisone depends on the form of the medication and the condition being treated. Creams, ointments, and solutions are usually applied to the affected area once or twice a day. Suppositories are inserted rectally and may be used multiple times a day. The dose for injections varies depending on the severity of the condition and is given under medical supervision.

Since corticosteroids like hydrocortisone are potent medications, they may cause side effects, especially if used for a prolonged period or in high doses. Common side effects include skin irritation, burning or itching at the application site, dry skin, acne, thinning of the skin, and changes in skin color. Systemic administration of hydrocortisone may lead to increased susceptibility to infections, delayed wound healing, increased blood sugar levels, weight gain, mood changes, insomnia, and osteoporosis.

It is important to use hydrocortisone exactly as prescribed by a healthcare professional and to follow the recommended duration of use. In case of any concerns about the medication or its side effects, it is advisable to consult a healthcare provider.

Calcium Dobesilate: Calcium Dobesilate is a medication that is primarily used to treat chronic venous insufficiency, a condition characterized by poor blood circulation in the veins. It is also sometimes prescribed for the treatment of diabetic retinopathy, a complication of diabetes that affects the blood vessels in the retina.

The mechanism of action of Calcium Dobesilate is not fully understood. However, it is believed to work by improving the strength and integrity of blood vessel walls and reducing inflammation. This helps to improve blood flow and reduce the symptoms associated with chronic venous insufficiency, such as pain, swelling, and leg ulcers.

The standard dose of Calcium Dobesilate is usually 500 mg to 1000 mg per day, divided into two to three doses. It is available in tablet or capsule form and is usually taken orally with or without food. The exact dosage may vary depending on the specific condition being treated and the patient’s response to the medication. It is important to follow the instructions provided by your healthcare provider and not to exceed the recommended dose.

Common side effects of Calcium Dobesilate include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and stomach pain. Some individuals may also experience skin rashes or itching. These side effects are usually mild and transient, but if they persist or become severe, it is important to consult a healthcare professional.

Rare but more serious side effects of Calcium Dobesilate may include allergic reactions such as difficulty breathing, chest tightness, and swelling of the face, lips, or tongue. If any of these symptoms occur, immediate medical attention should be sought.

It is important to note that Calcium Dobesilate should not be used in individuals with a known hypersensitivity to the drug or any components of the formulation. It is also not recommended for use in pregnant or breastfeeding women, unless specifically advised by a healthcare provider.

As with any medication, it is best to consult with a healthcare provider before starting Calcium Dobesilate to ensure it is appropriate for your specific condition and to discuss any potential drug interactions or contraindications.

Lidocaine (lignocaine Or Xylocaine): Lidocaine, also known as lignocaine or brand name Xylocaine, is a medication that belongs to the class of local anesthetics. It is commonly used to numb a specific area of the body for medical procedures, dental work, or to relieve pain and itching from conditions such as sunburn, insect bites, or minor burns.

The mechanism of action of lidocaine involves blocking nerve signals in a specific area of the body. Lidocaine works by binding to sodium channels on the nerve fibers, preventing the ions from entering the nerve cells. As a result, lidocaine inhibits the transmission of pain signals to the brain, thus producing a local anesthesia effect.

The dosage and method of administration of lidocaine can vary depending on the purpose and location of use. For example, it is available in various forms such as creams, ointments, gels, solutions for injection, or patches. The appropriate dose is determined by a healthcare professional based on the individual’s age, weight, and the specific condition being treated.

Common side effects of lidocaine may include temporary numbness or tingling at the site of application or injection. Other possible side effects include skin redness, itching, rash, or allergic reactions. If lidocaine is used in excessive amounts or accidentally injected into a blood vessel, it can cause serious side effects such as seizures, irregular heart rhythms, or breathing difficulties.

It is important to follow the instructions provided by the healthcare professional and avoid using lidocaine without medical supervision. Lidocaine should not be used on broken or infected skin or by individuals with a known allergy to lidocaine or related medications.

If any concerning side effects or allergic reactions occur after using lidocaine, medical attention should be sought immediately.

Troxerutin: Troxerutin is a drug that belongs to the class of medications known as flavonoids. It is commonly used as a vasoprotective agent and is derived from rutin, which is a natural bioflavonoid found in certain plants.

Troxerutin is primarily prescribed for the treatment of venous disorders, including chronic venous insufficiency, varicose veins, and hemorrhoids. It is also used to reduce edema and inflammation associated with these conditions. Additionally, troxerutin is sometimes used as a protective agent against oxidative stress and to enhance capillary resistance.

The exact mechanism of action of troxerutin is not fully understood. However, it is believed to work by strengthening the walls of blood vessels, improving blood flow, and reducing vascular permeability. Troxerutin also exhibits antioxidant properties, which help protect the blood vessels from oxidative damage.

Troxerutin is available in various dosage forms, including oral tablets, capsules, and gels. The recommended dose may vary depending on the indication and severity of the condition. Generally, the usual starting dose for adults is 300 mg to 1800 mg per day, to be taken in divided doses. It is important to follow the dosage instructions provided by your healthcare provider.

Like any medication, troxerutin may cause certain side effects. Common side effects may include gastrointestinal symptoms such as nausea, stomach discomfort, and diarrhea. Some individuals may experience allergic reactions, such as skin rash or itching. If any of these side effects persist or worsen, it is important to consult a healthcare professional.

It is essential to inform your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting troxerutin. They will be able to determine if it is safe for you to use this medication and recommend the appropriate dose.

In conclusion, troxerutin is a flavonoid-based medication commonly used for the treatment of venous disorders. It works by strengthening blood vessels and reducing vascular permeability. The recommended dose varies depending on the condition being treated. Common side effects may include gastrointestinal symptoms and allergic reactions.

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